Publications by authors named "Vaclav Kubes"
Article Synopsis
- - The study focuses on classic Hodgkin lymphoma (cHL), a common B-cell cancer, emphasizing that while many patients achieve remission with standard therapies, some relapse or have refractory disease, which raises concerns about long-term prognosis.
- - Researchers conducted a retrospective analysis involving 120 patients to study the relationship between PD-L1 expression on Hodgkin-Reed-Sternberg cells and patient outcomes, with a median follow-up of 90 months.
- - Results revealed that patients with positive PD-L1 expression had a higher relapse/refractory rate (28%) compared to those with negative expression, who did not experience any relapses, indicating that PD-L1 positivity is associated with poorer outcomes in cHL.
Gross pathology inspection (patho) is the gold standard for the morphological evaluation of focal myocardial pathology. Examination with 9.4 T magnetic resonance imaging (MRI) is a new method for very accurate display of myocardial pathology.
View Article and Find Full Text PDFBackground/aim: Glioblastoma (GBM) is one of the deadliest human cancers responding very poorly to therapy. Although the central nervous system has been traditionally considered an immunologically privileged site with an enhanced immune response, GBM appears to benefit from this immunosuppressive milieu. Immunomodulatory molecules play an important role in immune tumor-host interactions.
View Article and Find Full Text PDFCeliac disease is an immune mediated entheropathy triggered by gluten in genetically predisposed individuals. Patients with celiac disease are at a higher risk of gastrointestinal malignancies. Diagnosis at an advance stage is one of the factors of an unfavorable prognosis of these complications.
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