The Confusion Assessment Method in action: Implementation of a protocol to increase delirium screening and diagnosis.

The use of the Confusion Assessment Method (CAM) for delirium assessment in real-life can be inconsistent. We examined the impact of a protocol on delirium screening and detection in hospitalized older adults using the CAM. We analyzed data from 32,338 admissions to a quaternary hospital between 2018 and 2022.

Superacid Resin-Based Heterogeneous Catalysts for the Selective Acylation of 1,2-Methylenedioxybenzene.

In this work, we firstly report on the use of highly active and selective Aquivion superacid resins as heterogeneous catalysts for the acylation of 1,2-methylenedioxybenzene (MDB) with propionic anhydride (AP). The reaction was investigated and optimized using solvent-free conditions to selectively produce 3,4-methylenedioxypropiophenone (MDP1P), a key intermediate for the manufacture of active ingredients used in insecticide formulations with a volume of production of roughly 3000 t/y. Interestingly, Aquivion-based catalysts allows to work in mild reaction conditions (i.

Synaptic gradients transform object location to action.

To survive, animals must convert sensory information into appropriate behaviours. Vision is a common sense for locating ethologically relevant stimuli and guiding motor responses. How circuitry converts object location in retinal coordinates to movement direction in body coordinates remains largely unknown.

[Caseous calcification of the mitral annulus: case report and review of the literature].

Caseous calcification of the mitral annulus is an uncommon variant of mitral annular calcification. It appears as a round echodense mass containing central areas of echolucencies resembling liquefaction and with no flow in the central zone on color Doppler. In most cases it involves the posterior mitral annulus region, particularly in female subjects.

Impact of implementing good care and management practice guidelines in carotid revascularization procedures.

Background: Studies assessing the effect of implementing good practice management guidelines (GPMG) in carotid revascularization within the same hospital are scarce. Thus, we aimed to evaluate the impact of GPMG implementation on the clinical outcomes of carotid revascularization procedures within a quaternary hospital.

Method: We retrospectively studied 177 patients with atherosclerotic carotid disease who underwent revascularization (carotid endarterectomy and carotid artery stenting) at a quaternary hospital between January 2012 and December 2019.

Acute heart failure due to COVID-19 related myocardial injury and de novo hypertensive cardiomyopathy: a challenging diagnosis.

We report a COVID-19 case with acute heart and kidney failure in a healthy young male. Echocardiography showed severe systolic and diastolic left ventricle dysfunction, with diffuse myocardial thickening. Cardiac MRI showed aspects of focal myocarditis, and hypertensive cardiomyopathy.

Florence Nightingale: Legacy, present and perspectives in COVID-19 pandemic times.

Objective: Reflect on the influence of Florence Nightingale's teachings to face the COVID-19 pandemic and its repercussions for the future of the profession.

Methods: Descriptive reflective study, carried out between May and July 2020, through narrative review on the theme and debates between the authors.

Results: The findings are divided into two chapters, namely: Environmental Theory and the teachings of Florence Nightingale in the face of the COVID-19 pandemic; and Florence Nightingale: legacy, present and perspectives.

Course for the qualification of nurses in the care of children with genetic diseases: an experience report.

Objective: To describe the experience of developing and operating an extension course to qualify nurses in the care of children with genetic diseases.

Method: An experience report about the conduction of a university extension course with eight participants, developed at a public university in southern Brazil. It was a face-to-face course in November 2019.

Trajectories of obstetric nurses in the care of planned home childbirth: oral history.

Objective: To describe the trajectory of the insertion of obstetric nurses in the care of planned home childbirth in Rio Grande do Sul.

Method: An exploratory and qualitative study, with application of thematic oral history. Thirteen obstetric nurses who worked in planned home childbirth in the state participated in the study.

FeCrAl as a Catalyst Support.

The iron-chromium-aluminum alloy (FeCrAl) is an exceptional support for highly exothermic and endothermic reactions that operate above 700 °C in chemically aggressive environments, where low heat and mass transfer rates limit reaction yield. FeCrAl two- and three-dimensional structured networks-monoliths, foams, and fibers-maximize mass transfer rates, while their remarkable thermal conductivity minimizes hot spots and thermal gradients. Another advantage of the open FeCrAl structure is the low pressure drop due to the high void fraction and regularity of the internal path.

Implementation of a lesson plan model in the nursing laboratory: strengthening learning.

Objective: To describe the experience of implementing a lesson plan model for skills training as a learning tool in undergraduate nursing.

Method: An experience report on the implementation of a structured plan model for skills training in a nursing laboratory at a public university in southern Brazil. The activities were developed between May/2018 and April/2019.

Patient safety incidents reported by relatives of hospitalized children.

Objective: To know the main safety incidents reported by relatives of patients hospitalized in pediatric units.

Methods: This is a qualitative research with exploratory-descriptive design. Data were collected between April 2016 and December 2017, in three hospitals in Porto Alegre/RS.

End-of-life decision-making and advance care directives in Italy. A report and moral appraisal of recent legal provisions.

The present article reviews the state of public debate and legal provisions concerning end-of-life decision-making in Italy and offers an evaluation of the moral and legal issues involved. The article further examines the content of a recent law concerning informed consent and advance treatment directives, the main court pronouncements that formed the basis for the law, and developments in the public debate and important jurisprudential acts subsequent to its approval. The moral and legal grounds for a positive evaluation of this law, which attests that the patient may withhold or withdraw from life-prolonging treatment, will be offered with reference to liberal approaches and particularly to the frameworks of care and virtue ethics; but reasons will also be offered in order to consider not only the latter but also broader range of end-of-life treatment decisions as morally apt options.

A Plastic Visual Pathway Regulates Cooperative Behavior in Drosophila Larvae.

Cooperative behavior emerges in biological systems through coordinated actions among individuals [1, 2]. Although widely observed across animal species, the cellular and molecular mechanisms underlying the establishment and maintenance of cooperative behaviors remain largely unknown [3]. To characterize the circuit mechanisms serving the needs of independent individuals and social groups, we investigated cooperative digging behavior in Drosophila larvae [4-6].

Investigating the Optical Properties of a Laser Induced 3D Self-Assembled Carbon-Metal Hybrid Structure.

Carbon-based and carbon-metal hybrid materials hold great potential for applications in optics and electronics. Here, a novel material made of carbon and gold-silver nanoparticles is discussed, fabricated using a laser-induced self-assembly process. This self-assembled metamaterial manifests itself in the form of cuboids with lateral dimensions on the order of several micrometers and a height of tens to hundreds of nanometers.

MRI analysis to map interstitial flow in the brain tumor microenvironment.

Glioblastoma (GBM), a highly aggressive form of brain tumor, is a disease marked by extensive invasion into the surrounding brain. Interstitial fluid flow (IFF), or the movement of fluid within the spaces between cells, has been linked to increased invasion of GBM cells. Better characterization of IFF could elucidate underlying mechanisms driving this invasion .

2D Optical Gratings Based on Hexagonal Voids on Transparent Elastomeric Substrate.

A chromatic vectorial strain sensor constituted by hexagonal voids on transparent elastomeric substrate has been successfully fabricated via soft colloidal lithography. Initially a highly ordered 1.6 microns polystyrene spheres monolayer colloidal crystal has been realized by wedge-shaped cell method and used as a suitable mold to replicate the periodic structure on a polydimethylsiloxane sheet.

Publisher Correction: Functional aspects of meningeal lymphatics in ageing and Alzheimer's disease.

Change history: In this Article, Extended Data Fig. 9 was appearing as Fig. 2 in the HTML, and in Fig.

Get With The Guidelines®-Stroke performance indicators in patients with transient ischemic attack.

Objective: Get With The Guidelines®-Stroke is an in-hospital program for improving stroke care by promoting adherence to scientific guidelines. Of the patients with transient ischemic attack (TIA), 10-15% have a stroke within three months, and many patients do not receive the recommended interventions to prevent this outcome. The goal of this study was to assess the adherence to stroke quality indicators in patients with TIA.

Functional aspects of meningeal lymphatics in ageing and Alzheimer's disease.

Ageing is a major risk factor for many neurological pathologies, but its mechanisms remain unclear. Unlike other tissues, the parenchyma of the central nervous system (CNS) lacks lymphatic vasculature and waste products are removed partly through a paravascular route. (Re)discovery and characterization of meningeal lymphatic vessels has prompted an assessment of their role in waste clearance from the CNS.

Cooperative Behavior Emerges among Drosophila Larvae.

Spectacular examples of cooperative behavior emerge among a variety of animals and may serve critical roles in fitness [1, 2]. However, the rules governing such behavior have been difficult to elucidate [2]. Drosophila larvae are known to socially aggregate [3, 4] and use vision, mechanosensation, and gustation to recognize each other [5-8].

Patterns of Care and Temporal Trends in Ischemic Stroke Management: A Brazilian Perspective.

Background And Purpose: Demonstration of an improvement process of quality indicators in stroke care is essential to obtain certification as a primary stroke center (PSC). Our aim was to evaluate factors that influence temporal trends in quality indicators of ischemic stroke (IS) in a Brazilian hospital.

Methods: We evaluated patients discharged with IS from a tertiary hospital from January 2009 to December 2013.

Biomarkers of oxidative-stress and inflammation in exhaled breath condensate from hospital cleaners.

Objective: We studied the impact of chlorinated agents exposure on exhaled breath condensate (EBC) biomarkers in cleaners.

Methods: Malondialdehyde (MDA), 4-hydroxynonenal (4-HNE), nitrites (NO2(-)), nitrates (NO3(-)), pH, hydrogen peroxide (H2O2) and ammonium (NH3(+)) were tested in EBC of 40 cleaners and 40 non-exposed controls. Pentraxin-3 (PTX3) and soluble type II receptor of IL-1 (sIL-1RII) were analyzed also in plasma.