Prevalence of epilepsy in Croatia: a population-based survey.

Objectives: To investigate the prevalence of active epilepsy in Croatia.

Material And Methods: Patient data collected by means of questionnaires completed by primary healthcare physicians; epilepsy was previously confirmed in the patients by neurologists or neuropaediatricans.

Results: One hundred and twenty-seven of 180 (71%) physicians provided the requested information.

[Current results and methods in eradication of typhus fever on the Serbian territory excluding autonomic provinces].

Since 1969 Serbia has been conducting the programme of eradication louse-borne typhus. To this effect of Law on the eradication of communicable diseases has been passed. In addition to Republic Commission, as well as 6 regional commissions, and 18 communal commissions in whose territory the disease is being eradicated, have been formed.

Studies on vaccination against bacillary dysentery. 3. Effective oral immunization against Shigella flexneri 2a in a field trial.

In May 1963 a live vaccine prepared from streptomycin-dependent Shigella flexneri 2a was administered to 355 soldiers stationed in an area of Yugoslavia in which bacillary dysentery was hyperendemic. Five oral doses were given every third day. 382 unvaccinated soldiers from the same unit served as controls.

Studies on vaccination against bacillary dysentery. 2. Safety tests and reactogenicity studies on a live dysentery vaccine intended for use in field trials.

In view of the encouraging results obtained in active mouse protection experiments, several batches of live oral vaccine prepared from streptomycin-dependent Shigella flexneri were tested in vitro for any indication of reversion to streptomycin-independence and in man for their reactogenicity.The in vitro tests provided no evidence of reversion.In man, major reactions were observed in only 1.

Studies on vaccination against bacillary dysentery. 1. Immunization of mice against experimental Shigella infection.

In the course of a series of experiments begun in 1954 a number of different killed vaccines prepared from Shigella flexneri 1 and 2a serotypes were tested for their immunogenicity after intraperitoneal administration in mice followed by challenge with virulent organisms of the same serotype; some live vaccines were also tested intraperitoneally or orally.Maintenance of the mice on Freter's regimen proved a reliable method of rendering them susceptible to intestinal infection with streptomycin-resistant shigellae.Two killed vaccines conferred good protection against intracerebral challenge, but neither live nor killed vaccines administered intraperitoneally protected against oral infection of mice maintained on Freter's regimen.