[Correlation between empirical and statistical indices of cardiovascular deconditioning in response to orthostatic exposures].

Data of heart rate and blood pressure from 26 astronauts during orthostatic testing before and after space flight and 15 healthy men during orthostatic testing before and after 10-days head-down tilt (HDT) were used to correlate two integral indices of cardiovascular deconditioning. The first, very simple index, was used earlier by Bungo M. W.

[Contents of extracellular DNA in blood of irradiated rats].

Intact rat plasma contains high-molecular DNA which moves as a single fraction in 0.5% agarose electrophoresis. As early as 2-5 hours after gamma-irradiation in a dose of 1-100 Gy there appears low-molecular DNA (about 180 nucleotide pairs), the amount of which directly correlates with the irradiation dose 5 hours after the exposure.

[Detection of the determinants of tetracycline A, B and C resistance in Shigella and Salmonella using DNA probes].

Genetic determinants of tetracycline resistance of classes A, B and C were detected with DNA probes labeled with radioactive phosphorus (32P) in Shigella (44 strains) and Salmonella (50 strains). It was shown that in the Shigella strains the frequency of the Tet A gene amounted to 66 per cent, the frequency of the Tet B gene was equal to 84 per cent, the frequency of their combination was equal to 50 per cent and the frequency of the Tet C gene was nil. In the Salmonella strains the frequency of the Tet A, Tet B and Tet C genes was equal to 0.

[Information value of the indices of the nonspecific resistance of the body].

A number of nonspecific resistance characteristics in mice, such as the total number of peritoneal exudate cells, the percentage and absolute number of macrophages, their cytochemical activity in the spontaneous tetrazolium test and cytochemical capacity, have been studied by comparison with the resistance of the animals to tularemia infection induced by Francisella tularensis, Gaĭskiĭ's vaccinal strain 15. Of these characteristics, the cytochemical capacity of peritoneal exudate macrophages, i.e.

[Evaluation of the functional activity of peritoneal macrophages using the tetrazolium test].

The redox activity of peritoneal macrophages has been evaluated in the modified NBT test using tetranitro blue tetrazolium. This method permits the calculation of the total amount of peritoneal macrophages and the determination of their glass adherence per cent and their cytochemical activity value. The advantages of this method over the study of the phagocytic activity by means of phage T2 is shown.

[Factor analysis of reactions to lower body negative pressure on the earth and during space flight].

The method of main components was used to examine separately the cosmonauts' responses to LBNP tests on the ground and in space flight. The factor structures of the ground- and flight data did not show significant differences. In both cases the first factor can be termed the factor of venous return and the second, the factor of the cardiac state.

[Study of the variations in cardiovascular system indicators using the main component method].

The main component method was used to analyze measurements of cardiovascular parameters taken in 14 healthy operators at rest. The entire sample included 237 observations. Each observation was characterized by the deviation of heart rate, mean blood pressure and stroke volume from individual data points.

[Changes in cardiac output and orthostatic tolerance of astronauts].

Examinations of 14 cosmonauts who performed orbital flights of 14 to 175 days were used to correlate cardiac output (CO) inflight with orthostatic tolerance and LBNP reactions postflight. In 3 crewmembers CO was lower than or close to the preflight level. In 4 cosmonauts CO was higher thant preflight.

[Migration of the ampicillin transposon in enteropathogenic Escherichia].

Migration of Tn 1 from plasmid RP4 into the chromosome of enteropathogenic Escherichia (EPE) of serogroups O124 and O111 was studied. E. coli K 12 LC 411 (RP4) was used as the donor.

[Phagocytosis of enteropathogenic escherichiae of serogroup 0124:K72(B17)].

Experiments with phagocytosis of E. coli O124 in the macrophage tissue culture demonstrated a different phagocytability of the S- and R-forms of these bacteria determined by their concentration in the medium. The ingestive and digestive capacity depended on the bacterial virulence.