[Basophil "degranulation" as an index of the body stress state].

A regular "degranulation" development of basophilic leucocytes in the blood has been established not only in cases of the joint and skin allergic reactions but in acute and chronic experimental hemorrhage, skin burns and acute radiation disease. Basophilic "degranulation" denotes the stress state of the organism as a result of stress situations.

[Use of paper indicator discs for determining the minimal inhibitory concentration of antibiotics].

Sensitivity of clinical strains of Staphylococcus and some Enterobacteriaceae to a number of widely used antibiotics was compared simultaneously with the use of two methods, i. e. the agar diffusion method and the method of serial dilutions.

[Evaluation of the changes of natural resistance in patients with diffuse peritonitis].

A suppression of humoral and cell mechanisms of natural nonspecific resistance was found in patients with diffuse peritonitis. A considerable degranulation of basophilic leucocytes was indicated by the direct Shelley reaction, that evidences alterations in the functional state of these cells. Postoperatively, there is a break in restoration of the activity of properdine and its cofactors, and a considerable suppression of the phagocytic capacity of microphages is noted, that leads inevitably to a reduction of immune reactivity.

[The functional activity of microphages and cation protein in experimental allergic arthritis].

A reduction of the content of cation protein in microphages was revealed in experimental allergic arthritis with the aid of the fluorescent-microscopic method of cation protein detection and objective recording of its content. Phagocytic activity of these cells diminished in parallel with reduction of the cation protein content. Protective properties of microphages were possibly reduced as a result of allergic alteration of cells leading to their structural and functional reconstruction.