Aminoglutethimide (AG) is a drug that inhibits steroid synthesis; it is used in advanced breast cancer. After the observation of abnormalities in lipid metabolism in patients, we realized an experimental study to try to look for a pathogenetic hypothesis. Three groups of rats received respectively AG, Hydrocortisone (HC) or both (AG + HC) and were compared to controls.
View Article and Find Full Text PDFC R Seances Soc Biol Fil
December 1977
The blood and liver giver animals are given "Tromexan" for a period of three days. The blood defibrination is finished off by shaking. The perfusion is made of defibrinated blood to which is added a compounding of mineral salts, albumin and glucose in adequate proportions.
View Article and Find Full Text PDFC R Seances Soc Biol Fil
April 1976
Hypothermia inhibits the (Na+ K+) ATPase but does not decrease the concentrations of Na in bile when NaCl is added to the perfusate. With ouabaïne, another inhibitor of (Na+ K+) ATPase, we had previously seen decrease of sodium excretion. This discrepancy might be the result of an increase excretion in bile acids during hypothermia.
View Article and Find Full Text PDFC R Seances Soc Biol Fil
January 1975
C R Acad Hebd Seances Acad Sci D
September 1972
C R Seances Soc Biol Fil
April 1973
J Physiol (Paris)
September 1972
C R Acad Hebd Seances Acad Sci D
July 1968