Publications by authors named "V. Rajesh Kannan"

A metagenomic approach was employed to investigate the diversity and distribution of Virulence Factors Genes (VFGs) and Pathogenic Bacteria (PB) in sediment samples collected from highly urbanized cities along the Indian coastline. Among the study locations, Mumbai, Veraval and Paradeep showed a higher abundance of PB, with Vibrio and Pseudomonas as dominant at the genus level, and Escherichia coli and Pseudomonas aeruginosa at the species level. In total, 295 VFGs were detected across all sediment samples, of which 40 VFGs showed a similarity of ≥90 % with the Virulence Database (VFDB) and were focused in this study.

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Three simple dipodal artificial acyclic symmetric receptors, , , and , driven by positional isomerism based on xylelene scaffolds were designed, synthesized, and characterized by H NMR, C NMR, and mass spectroscopy techniques. Probes , , and demonstrated selective detection of Ag metal ions and amino acid l-histidine in a DMSO-HO solution (1:1 v/v, HEPES 50 mM, pH = 7.4).

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In recent years, wide spread of antibiotic-resistant microorganisms and genes emerging globally, an eco-friendly method for efficient degradation of antibiotics from the polluted environment is essential. Intimately coupled photocatalysis and biodegradation (ICPB) using gCN for enhanced degradation of sulfamethoxazole (SMX) was investigated. The gCN were prepared and coated on the carbon felt.

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Clinical pathogens, especially Gram-negative bacteria developing resistance to third-generation cephalosporins, are making clinical outcomes more complicated and serious. This study was undertaken to evaluate the distribution of CTX-M-type extended-spectrum β-lactamases (ESBLs) in Tamil Nadu, India. For this study, clinical samples were collected from five different hospitals located in Tamil Nadu and the ESBL-producing Gram-negative isolates were characterized.

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Diuron is one of the major hazardous pollutants which posses severe risk to the environment and human healthiness. On the other hand, salinity is the most severe environmental stressor that limits crop productivity. Therefore, it is required to address this co-existing abiotic stresses in agricultural soil.

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Aluminum (Al) is a major constraint for plant growth by inducing inhibition of root elongation in acid soils around the world. Besides, drought is another major abiotic stress that adversely affects growth and productivity of agricultural crops. The plant growth-promoting (PGP) rhizobacterial strains are useful choice to decrease these stressful effects and is now extensively in practice.

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Curcumin delivery to cancer cells is challenging due to its hydrophobic nature, low bio distribution and low availability. Many nano vehicles suffer from low stability and toxicity, and hence the prerequisite of a non-toxic nano vehicle with effective drug delivery is still being delved. The present study investigates the delivery efficiency of curcumin with non-spherical mesoporous silica nanoparticles (MSNAs).

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The capability of plant growth promoting microbes to survive under abiotic stresses has important significance for improving plant growth and productivity. Among the various plant growth promoting biomolecules produced by microbes, exopolysaccharide (EPS) help microbes to survive in inhospitable environments and endure environmental stressful conditions. In the present study, a yeast strain CAH2 was isolated from Beta vulgaris rhizosphere soil and identified as Rhodotorula sp.

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Curcumin is an active compound extracted from the rhizomes of Curcuma longa L. (Turmeric). It possesses a di phenolic structure and there are three important fractions of curcumin namely curcumin, mono-desmethoxycurcumin and bis-desmethoxycurcumin.

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Polyhydroxyalkanoate (PHA) is the biodegradable plastic, which is shown the similar properties to the synthetic plastic. Production of PHA is expensive when compared with petrochemical based plastics costs and also hazardous to ecosystem. In order to overcome these drawbacks, some cheaper commercially available carbon sources like rice bran, coconut cake, palm jaggary, etc.

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Endoplasmic reticulum (ER) stress-mediated apoptosis is a well-known factor in the pathogenesis of age-related macular degeneration (AMD). ER stress leads to accumulation of misfolded proteins, which in turn activates unfolded protein response (UPR) of the cell for its survival. The prolonged UPR of ER stress promotes cell death; however, the transition between adaptation and ER stress-induced apoptosis has not been clearly understood.

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The Cr(6+)-resistant plant growth-promoting bacteria was isolated from soil samples that were collected from an electroplating industry at Coimbatore, India, that had tolerated chromium concentrations up to 500 mg Cr(6+)/L in Luria-Bertani medium. Based on morphology, physiology, and biochemical characteristics, the strain was identified as Bacillus sp. following the Bergey's manual of determinative bacteriology.

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Capparis sepiaria Linn. (Family: Capparidaceae) is a rare indigenous in South India but has widespread distribution in many tropical and sub-tropical countries. The present study intended with various phytochemical screening and toxicity studies were carried out on the leaves of the Capparis sepiaria.

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