Publications by authors named "V Zimmer"

Background: Most spheroid models use size measurements as a primary readout parameter; some models extend analysis to T cell infiltration or perform caspase activation assays. However, to our knowledge, T cell motility analysis is not regularly included as an endpoint in imaging studies on cancer spheroids.

Methods: Here, we intend to demonstrate that motility analysis of macrophages and T cells is a valuable functional endpoint for studies on molecular interventions in the tumor microenvironment.

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Article Synopsis
  • The study analyzed data from 2013 to 2021 on patients with acute pancreatitis (AP) in a Chinese city, revealing an increase in cases linked to hypertriglyceridemia and alcohol consumption while the prevalence of biliary-related AP remained stable.
  • An increase in severe acute pancreatitis (SAP) cases was noted, with a rise in prevalence from 4.97% to 12.2% over the years, and male patients were found to have a higher occurrence of AP compared to females.
  • Additionally, the median length of stay and hospitalization costs significantly decreased, while the overall in-hospital mortality rate remained constant throughout the study period.
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