[Characteristics of lipid peroxidation and activity of sympathetic nervous system in patients with chronic calculous pyelonephritis].

108 patients (89 women and 19 men) aged from 18 to 59 years with chronic pyelonephritis (CP) on the background of urolithiasis in a phase of active inflammation were evaluated. Along with the standard methods of examination, survey plan included the use of specific biochemical diagnostic methods. The latter included an evaluation of lipid peroxidation, the level of fat-soluble antioxidant alpha-tocopherol, fractions of phospholipids and cholesterol in the membranes of polymorphonuclear leukocytes (PMN).

[Comparative effectiveness of fluoroquinolones and beta-lactams in the complex therapy of patients with chronic pyelonephritis].

A comparative study has evaluated the effect of fluoroquinolones and beta-lactams on clinical and biochemical manifestations of chronic pyelonephritis (CPN). 108 patients aged from 18 to 59 years (mean age - 40.26 +/- 10.

[Immunological indices in urolithiasis patients with secondary pyelonephritis].

The immunological status was studied in 335 patients with urolithiasis and pyelonephritis. The techniques used for assessment of the immunological status provided a multifactorial control over immune system function in inflammation and urolithiasis: registered a significant rise of the level of proinflammatory and anti-inflammatory mediators of the immune response (IL-1beta, IL-4, IL-6, TNF), of neutrophil metabolic activity with parallel suppression of neutrophil phagocytic and absorbing functions, inhibition of bactericidal activity of the serum, a significant fall in the number of mature T-lymphocytes (CD3+) and T-helpers (CD4+). The immune status indices in urolithiasis patients with secondary pyelonephritis are closely linked with clinico-laboratory manifestations of the inflammatory process and renal function.

[Polyoxidonium in the treatment of calculous pyelonephritis].

Efficacy of polyoxidonium was studied in combined therapy of urolithiasis complicated with secondary pyelonephritis. Of 60 patients with secondary pyelonephritis in urolithiasis, 30 received adjuvant polyoxidonium. Phospholipids and cholesterol in cytomembranes were defined with thin-layer chromatography.