Publications by authors named "V Zagonel"

Lynch syndrome is rarely associated with rectal cancer (RC) and thus, metachronous RC has been scarcely investigated. This study aimed to analyze the mucosal immune microenvironment in sporadic and metachronous RC. We analyzed the mucosal immune microenvironment in the 25 metachronous RCs present in the IMMUNOREACT 1 and 2 multicentre observational studies (624 patients).

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Article Synopsis
  • Early palliative care (EPC) is essential for improving the quality of life for advanced cancer patients and their caregivers, but research on psychological evaluations in EPC is limited.
  • A study at the Veneto Institute of Oncology evaluated psychological needs and symptoms in 753 patients, finding that over half reported psychological symptoms, with significant instances of depression and anxiety.
  • The study revealed discrepancies between oncologists' estimates of patients' psychological symptoms and the patients’ self-reports, highlighting the need for better integration of psychological support in the palliative care team.
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Background: Palliative surgery (PS) is defined as any surgical procedure aimed at improving quality of life or relieving symptoms caused by an advanced or metastatic cancer. The involvement of patients, caregivers, and other professional figures is crucial for obtaining optimal symptom relief and avoiding complications. This study aims to evaluate the short-term outcome and related factors in patients undergoing PS.

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Background: Long-term daily use of aspirin reduces incidence and mortality due to colorectal cancer (CRC). This study aimed to analyze the effect of aspirin on the tumor microenvironment, systemic immunity, and on the healthy mucosa surrounding cancer.

Methods: Patients with a diagnosis of CRC operated on from 2015 to 2019 were retrospectively analyzed (METACCRE cohort).

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