Publications by authors named "V Zaccaria"
Strategies for controlling cholesterol and lipid metabolism, including the use of food supplements, are part of the non-pharmacological intervention to ameliorate cardiovascular health. To demonstrate the efficacy of a standardized flavonoids (150 mg/day) extract from on cholesterol and lipid management, a placebo-controlled clinical trial on 64 subjects with high cholesterol was carried out. The total study duration was 4 months, with intermediate checkpoints at 1-month intervals.
View Article and Find Full Text PDFCognitive decline, a common consequence of aging, detrimentally affects independence, physical activity, and social interactions. This decline encompasses various cognitive functions, including processing speed, memory, language, and executive functioning. This trial aimed to investigate, with a double-blind, placebo-controlled clinical trial on 96 healthy older adults, the efficacy of once-daily 250 mg of a standardized grape ( L.
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- Multiple Complex Developmental Disorder (MCDD) is a condition that affects various areas of development and could be seen as lying between autism and childhood-onset schizophrenia, but interest in it has decreased over time.
- This study systematically reviewed literature on MCDD to evaluate its current significance, finding only 16 relevant studies that varied widely in methodology and focus.
- The analysis revealed that children with MCDD tended to experience more paranoia and psychotic symptoms compared to those with autism, highlighting a potential diagnostic gap that warrants further investigation.
The practical and easy detection of dopamine levels in human fluids, such as urine and saliva, is of great interest due to the correlation of dopamine concentration with several diseases. In this work, the one-step synthesis of water-soluble carbon nanoparticles (CNPs), starting from artichoke extract, containing catechol groups, for the fluorescence sensing of dopamine is reported. Size, morphology, chemical composition and electronic structure of CNPs were elucidated by DLS, AFM, XPS, FT-IR, EDX and TEM analyses.
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- Functional neurological symptom disorders (FNSD) are commonly encountered in clinical practice, especially in children, and can be mistaken for other medical issues due to their complex symptoms.
- The review contrasts FNSD with various psychiatric and neurological disorders, clarifying that FNSD should be viewed as a diagnosis of inclusion, not just exclusion based on overlapping symptoms.
- A key case study of a 14-year-old boy initially diagnosed with FNSD, later found to have paroxysmal kinesigenic dyskinesia, highlights the need for thorough assessment to avoid misdiagnosing FNSD and to identify true underlying conditions.