Hybrid Complexes of Photosensitizers with Luminescent Nanoparticles: Design of the Structure.

Increasing the efficiency of the photodynamic action of the dyes used in photodynamic therapy is crucial in the field of modern biomedicine. There are two main approaches used to increase the efficiency of photosensitizers. The first one is targeted delivery to the object of photodynamic action, while the second one is increasing the absorption capacity of the molecule.

Temperature Dependence of Tryptophan Fluorescence Lifetime as an Indicator of Its Microenvironment Dynamics.

The spectral-kinetic characteristics of the fluorescence of the tryptophan molecule in an aqueous solution and in the composition of a protein (albumin) were studied in the temperature range from -170 to 25°C. To explain the observed changes in the spectra and the tryptophan fluorescence lifetime with temperature, a model of transitions between the excited and ground states involving a charge-transfer state was used, which takes into account the nonlinear nature of the dynamics of these transitions. In these processes, an important role is played by the interaction of tryptophan molecules with its microenvironment, as well as rearrangements in the system of hydrogen bonds of the water-protein matrix surrounding the tryptophan molecule.

Photophysical Properties of Upconverting Nanoparticle-Phthalocyanine Complexes.

Interaction between upconverting nanoparticles and aluminum octacarboxyphthalocyanine was studied. The efficiency of non-radiative energy transfer from the nanoparticles to phthalocyanine increased with the number of phthalocyanine molecules adsorbed on the nanoparticle, but only up to a certain limit. Further increase in the phthalocyanine concentration resulted in a decrease of its sensitized fluorescence due to the dimerization of dye molecules on the nanoparticle surface.

[Business planningas as a tool for reforming PНС].

Objective: Introduction: The reform of primary health care (PHC), the introduction of market mechanisms in health care, and the consequent change in the status of primary health care institutions require new approaches to the organization and management of the sector. This work is related to various aspects of health care reform: organizational, medical, social, production, financial, economic, etc. The aim of the research is to substantiate the need to apply the principles of business planning for the reform of PHC, in particular: аs a method of strategic planning and operational management of the production activities of a medical institution, аs a way of preventing and solving problems arising from the reform of the industry, аs an instrument for attracting external capital required for project implementation, аs a way of development of personal managerial qualities of the authors of the project - the head of a medical institution and his deputies.

Magneto-optical properties of terbium iron borate.

The Faraday effect induced by an external magnetic field in TbFe₃(BO₃)₄ and TbAl₃(BO₃)₄ borates at a wavelength 633 nm has been investigated. It was found that the terbium subsystem brings the dominant magnetic contribution to the Faraday rotation at low temperatures in borate TbFe₃(BO₃)₄. For both TbFe₃(BO₃)₄ and TbAl₃(BO₃)₄ the magneto-optical coefficients of the terbium subsystem were determined.