Publications by authors named "V Yu Fedorov"

This study addresses issues in developing spatially controlled magnetic fields for particle guidance, synthesizing biocompatible and chemically stable MNPs and enhancing their specificity to pathological cells through chemical modifications, developing personalized adjustments, and highlighting the potential of tumor-on-a-chip systems, which can simulate tissue environments and assess drug efficacy and dosage in a controlled setting. The research focused on two MNP types, uncoated magnetite nanoparticles (mMNPs) and carboxymethyl dextran coated superparamagnetic nanoparticles (CD-SPIONs), and evaluated their transport properties in microfluidic systems and porous media. The original uncoated mMNPs of bimodal size distribution and the narrow size distribution of the fractions (23 nm and 106 nm by radii) were demonstrated to agglomerate in magnetically driven microfluidic flow, forming a stable stationary web consisting of magnetic fibers within 30 min.

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O-centered tetranuclear vanadium selenoiodide [VOSeI] (1) was synthesized by an ampoule method from the elements with addition of water. Its X-ray crystal structure (space group 2/, = 21.146(2) Å, = 5.

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Thin (~50 nm thick) BaM hexaferrite (BaFeO) films were grown on (1-102) and (0001) cut α-AlO (sapphire) substrates via laser molecular beam epitaxy using a one- or two-stage growth protocol. The advantages of a two-stage protocol are shown. The surface morphology, structural and magnetic properties of films were studied using atomic force microscopy, reflected high-energy electron diffraction, three-dimensional X-ray diffraction reciprocal space mapping, powder X-ray diffraction, magneto-optical, and magnetometric methods.

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Article Synopsis
  • Dermal fibroblasts (DFs) from hypertrophic scars (HTSFs) show higher proliferation and motility compared to those from normal skin (NDFs), despite minor karyotype differences.
  • A detailed proteomic analysis revealed unique metabolic proteins in HTSFs that could explain their aggressive behavior and links to scarring.
  • Identified proteins related to cell growth, movement, fibrosis, and inflammation suggest potential targets for future treatments or prevention strategies for skin scarring.
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