Phase disposition PWM control topology based: A novel multilevel inverter with reduced switch for power electronics applications.

In the field of industrial drive applications, a neutral point clamped multilevel inverter (NPC MLI) is an extensively used option. The NPC MLI architecture involves more number of components for higher level and higher switching frequency operation. In this work paper, a novel three-phase 3-Level MLI is proposed evading the usage of clamping diodes and quadratic switches.

Effectiveness of Ultraviolet Radiation and Disinfectant Wipes in Reducing the Microbial Contamination of Mobile Phones in a Tertiary Care Hospital.

Background As mobile phones act as a potential source of microbial contamination, particularly in a hospital environment, the effectiveness of two most debated interventions namely ultraviolet radiation and disinfectant wipes in reducing the microbial contamination of mobile phones is compared. Objective To screen the mobile phones of healthcare personnel for the presence of microorganisms and to compare the effectiveness of ultraviolet radiation and disinfectant wipes in reducing microbial contamination. Methods and materials Pre-intervention and post-intervention swabs were collected before and after the use of each intervention respectively using 56 samples and cultured for growth in nutrient agar.

The Clinical Profile of Newly Diagnosed Acute Myeloid Leukemia at a Tertiary Care Center in South India: A Cross-Sectional Study.

Background and objective Acute myeloid leukemia (AML) is a heterogeneous and aggressive blood malignancy prevalent among both children and adults, accounting for a significant proportion of acute leukemia cases worldwide. Our study aimed to shed light on the demographic and clinical profile and risk stratification of newly diagnosed AML cases at a tertiary care government hospital in South India. Methods We conducted a cross-sectional study involving 221 patients with AML in the Department of Clinical Hematology, Rajiv Gandhi Government General Hospital and Madras Medical College, Chennai, Tamil Nadu from January 2020 to December 2022.

Circulating small extracellular vesicles in Alzheimer's disease: a case-control study of neuro-inflammation and synaptic dysfunction.

Background: Alzheimer's disease (AD) is a neurodegenerative disease characterized by Aβ plaques and neurofibrillary tangles. Chronic inflammation and synaptic dysfunction lead to disease progression and cognitive decline. Small extracellular vesicles (sEVs) are implicated in AD progression by facilitating the spread of pathological proteins and inflammatory cytokines.