Publications by authors named "V Wolff"
The anti-inflammatory and analgesic properties of cannabis might be useful to treat muscle diseases, including those linked or not to alcohol. Nevertheless, delta 9 tetrahydrocannabinol (THC) and ethanol (EtOH), often used concomitantly, can have deleterious effects on cardiac mitochondria. We therefore determined whether EtOH, alone and associated with THC, impairs skeletal muscle mitochondrial respiration.
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- The study investigated the clinical and radiological factors affecting the outcomes of acute ischemic stroke patients with isolated posterior cerebral artery (PCA) occlusion treated only with medical management.
- A total of 585 patients were analyzed, revealing that 56% experienced poor functional outcomes, which were linked to older age, higher NIHSS scores, larger infarct volumes, and not receiving intravenous thrombolysis (IVT).
- The research highlighted that factors like age, NIHSS score, infarct volume, and IVT status significantly influenced outcomes, while finding that complete recanalization after 24 hours improved recovery chances.
Stroke-related restless legs syndrome (sRLS) is an emerging clinical entity, with a clear relationship between stroke and the occurrence of restless legs syndrome (RLS). Dopamine dysregulation has been observed in sRLS of the lenticulostriate region with increased dopamine precursor and decreased dopamine transporter. The aim of this work is to explore an original case of regressive RLS following stroke.
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- Patients with immunodeficiency are at a higher risk of developing certain cancers, particularly mature lymphoid neoplasms and lymphoproliferative disorders.
- A 50-year-old woman on immunosuppressive therapy for dermatomyositis presented with swollen lacrimal glands, weight loss, and night sweats, leading to an elective biopsy.
- Post-surgery, she experienced acute abdominal issues that revealed multiple organ lesions and ultimately led to a diagnosis of polymorphic B-lymphoproliferative disorder resembling lymphomatoid granulomatosis, a rare condition linked to immunosuppression.
Background: The use of thrombectomy in patients with acute stroke and a large infarct of unrestricted size has not been well studied.
Methods: We assigned, in a 1:1 ratio, patients with proximal cerebral vessel occlusion in the anterior circulation and a large infarct (as defined by an Alberta Stroke Program Early Computed Tomographic Score of ≤5; values range from 0 to 10) detected on magnetic resonance imaging or computed tomography within 6.5 hours after symptom onset to undergo endovascular thrombectomy and receive medical care (thrombectomy group) or to receive medical care alone (control group).