Publications by authors named "V Wens"

Objective: Intracranial single-pulse electrical stimulation (SPES) can elicit cortico-cortical evoked potentials. Their investigation with intracranial EEG is biased by the limited number and selected location of electrodes, which could be circumvented by simultaneous non-invasive whole-scalp recording. This study aimed at investigating the ability of magnetoencephalography (MEG) to characterize cortico-cortical evoked fields (CCEFs) and effective connectivity between the epileptogenic zone (EZ) and non-epileptogenic zone (i.

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Magnetoencephalography (MEG) measures brain function via assessment of magnetic fields generated by neural currents. Conventional MEG uses superconducting sensors, which place significant limitations on performance, practicality, and deployment; however, the field has been revolutionised in recent years by the introduction of optically-pumped magnetometers (OPMs). OPMs enable measurement of the MEG signal without cryogenics, and consequently the conception of "OPM-MEG" systems which ostensibly allow increased sensitivity and resolution, lifespan compliance, free subject movement, and lower cost.

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Article Synopsis
  • This study investigates the variability of cortico-cortical evoked potentials (CCEPs) during single-pulse electrical stimulations to understand their relationship with seizure activity in patients with epilepsy.
  • Researchers analyzed data from 20 patients with a focus on how CCEP measurements changed in relation to the location of the epileptogenic zone (EZ) and the occurrence of interictal discharges.
  • Findings indicate that increased seizure frequency correlates with decreased variability in CCEP measurements, suggesting that the epileptogenic network becomes more interconnected with frequent seizures, emphasizing the need for timely epilepsy surgery.
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Objective: To investigate cortical oscillations during a sentence completion task (SC) using magnetoencephalography (MEG), focusing on the semantic control network (SCN), its leftward asymmetry, and the effects of semantic control load.

Methods: Twenty right-handed adults underwent MEG while performing SC, consisting of low cloze (LC: multiple responses) and high cloze (HC: single response) stimuli. Spectrotemporal power modulations as event-related synchronizations (ERS) and desynchronizations (ERD) were analyzed: first, at the whole-brain level; second, in key SCN regions, posterior middle/inferior temporal gyri (pMTG/ITG) and inferior frontal gyri (IFG), under different semantic control loads.

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Magnetoencephalography (MEG) measures brain function via assessment of magnetic fields generated by neural currents. Conventional MEG uses superconducting sensors, which place significant limitations on performance, practicality, and deployment; however, the field has been revolutionised in recent years by the introduction of optically-pumped-magnetometers (OPMs). OPMs enable measurement of the MEG signal without cryogenics, and consequently the conception of 'OPM-MEG' systems which ostensibly allow increased sensitivity and resolution, lifespan compliance, free subject movement, and lower cost.

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