J Soc Gynecol Investig
January 1998
Objective: We sought to determine whether the immunohistochemical detection of epidermal growth factor receptor (EGF-R) in primary cancer tissues is of prognostic significance in patients with breast carcinoma.
Methods: Paraffin-embedded tissues from 244 study subjects with primary breast carcinomas were tested immunohistochemically for the presence of EGF-R and were compared in a retrospective study with clinical outcome.
Results: Epidermal growth factor receptor was detected in the tumors of 49 (20.