Traumatic pediatric cervical spine injury-a proposed clearance algorithm incorporating a 24-h time delay.

Purpose: Pediatric cervical spine injury (pCSI) is rare. Physiological differences necessitate alternate management from adults. Yet, no standardized pediatric protocols exist.

Functional and phylogenetic signals in the pectoral girdle of Thalattosuchia and Dyrosauridae (Crocodylomorpha).

Crocodylomorphs have colonized various environments from fully terrestrial to fully aquatic, making it an important clade among archosaurs. A remarkable example of the rich past diversity of Crocodylomorpha Hay, 1930 is the marine colonization undergone by several crocodylomorph lineages, particularly Thalattosuchia Fraas, 1901 during the Early Jurassic-Early Cretaceous, and Dyrosauridae de Stefano, 1903 during the Late Cretaceous-Early Eocene. Thalattosuchia represents the most impressive and singular marine radiation among Crocodylomorpha, occupying various ecological niches, before enigmatically disappearing in the Cretaceous.

Intercellular, Linear Direct Immunofluorescence Staining Pattern of Sweat Glands and Hair Follicles may be Used as a Diagnostic Marker for Pemphigus Vulgaris in Cases where Epidermis is Missing.

Due to its rarity, it takes months for patients to be correctly diagnosed with pemphigus vulgaris. This delay can be exacerbated by factors such as incorrect biopsy site selection. When the epidermis detaches from the dermis, evaluating fluorescence patterns is impossible.

Does voluntary practice improve the outcome of an OSCE in undergraduate medical studies? A Propensity Score Matching approach.

In Objective Structured Clinical Examinations (OSCE), students have to demonstrate proficiency in a wide array of medical knowledge and different skills, ranging from physical examinations to medical-practical skills and doctor-patient interactions. In this study, we empirically test the concept 'assessment drives learning' and investigate whether an OSCE motivates extracurricular, voluntary free practice (FP) of specific skills in a Skills Lab, and whether this has positive treatment effects on exam success in the respective parts of the OSCE. To explore causal inference with observational data, we used Propensity Score Matching (PSM) to generate a control and a treatment group that only differed in their practice behavior.

On the identification of differentially-active transcription factors from ATAC-seq data.

ATAC-seq has emerged as a rich epigenome profiling technique, and is commonly used to identify Transcription Factors (TFs) underlying given phenomena. A number of methods can be used to identify differentially-active TFs through the accessibility of their DNA-binding motif, however little is known on the best approaches for doing so. Here we benchmark several such methods using a combination of curated datasets with various forms of short-term perturbations on known TFs, as well as semi-simulations.