Publications by authors named "V Vazgiourakis"

Article Synopsis
  • Critically ill patients in the ICU often develop new-onset atrial fibrillation (NOAF), which is linked to higher mortality rates; however, it's not clear if NOAF is a sign of illness severity or a direct cause of worse outcomes.
  • The study analyzed 685 mechanically ventilated patients over three years to identify the incidence of NOAF and its relationship with mortality, particularly focusing on those without preexisting conditions that predispose them to the condition.
  • Results showed that 16.1% of patients developed NOAF, primarily due to septic episodes, with older age and a history of hypertension also contributing, indicating that sepsis is a major independent factor associated with the onset of NOAF.
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Sepsis is an insidious and frequent condition of severe inflammation due to infections. Several biomarkers have been established for initial screening, but the non-specific nature of the existing biomarkers has led to the investigation of more sensitive and specific tools, such as microRNAs (miRs). These non-coding RNAs are involved in several diseases, including sepsis, due to their roles in cellular homeostasis.

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Objectives: To evaluate hemodynamic profiles of critical care patients undergoing spontaneous t-piece trial (SBT) and present weaning failure.

Methods: Prospective observational study conducted in ready-to-wean non-cardiac ICU patients. Clinical, echocardiographic and thermodilution-derived variables were recorded before and after a 2-hour SBT.

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Background: Sepsis is a life-threatening organ dysfunction, and septic cardiomyopathy (SCM) may complicate the course of the disease. Infection with multidrug-resistant (MDR) pathogens has been linked with worse outcomes. This study aims to evaluate SCM in patients with infections caused by different antimicrobial-resistant phenotypes.

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