[Thyroid hormone dynamics during the thyrostatic treatment of Basedow's disease].

The efficacy of the generally accepted therapeutic scheme was studied in 52 newly discovered and untreated patients with Basedow's disease with the purpose to clarify the frequent failures of the thyrostatic treatment. The thyroid hormones levels were determined in dynamics initially and in the course of the disease. The results show that the efficacy of the thyrostatic drugs is individually different and depends on the supersensitivity of the thyroid gland.

[A case of Pendred's syndrome].

A very rate case of a combination of congenital deaf-mutism and sporadic goiter due to peroxidase insufficiency is presented. This condition is known as Pendred's syndrome. The special features of the case requiring surgical treatment in contrast to the generally accepted conservative attitude are pointed out.

[The TRH test using the Bulgarian preparation Protilerin in the diagnosis of hyperthyroidism].

The stimulation test--TRH test was carried out with the Bulgarian drug "Protilerin" in 63 patients (Basedow's disease--53 patients, basedoid goiter--5 patients, infiltrative ophthalmopathy--5 patients) and in 20 healthy controls. The healthy controls showed normal reaction to the stimulation. All patients with hyperthyroidism showed a suppressed response to the stimulation.

[Dynamic thyroid hormone levels during the thyrostatic treatment of Basedow's disease].

The thyroid hormones and thyrotropic hormone levels were followed up dynamically in the course of thyrostatic treatment in 24 newly discovered patients with Basedow's disease. The following findings deserve special attention: 1. The early appearance of therapeutic remission--mean after 2.

[Clinical results with a complex conservative treatment method in infiltrative ophthalmopathy (preliminary report)].

The present methods for the treatment of infiltrative ophthalmopathy are still unsatisfactory, some of them associated with considerable and lasting side effects. Clinical results are present in the communication, from the application of an original therapeutic complex, consisting in the parallel administration of ACTH, intravenous infusions, moderate doses cortison, diuretics and sanation via antibiotics and eventual surgical intervention of the existing focal infectious agents. The complex is applied in the course of 4 weeks.