[Sensitivity of patients to immunomodulators in immunodeficiency diseases].

There were examined 198 patients, in whom immunodeficient (inflammatory, infectious and viral) diseases were revealed, as well as 10 healthy persons--for investigation of sensitivity of the blood neutrophils to immunomodulators (timalin, immunofan, polyoxidonium, timogen, erbisol). Most active one, in accordance to the investigation data, have evolved a synthetic preparation polyoxidonium, action mechanism of which is caused by direct activating impact on phagocytosis. Absence of sensitivity of the blood neutrophils towards activating stimuli (immunomodulators) in some patients was caused by a phenomenon, according to which the blood neutrophils, persisting durably in a preactivated state, further (while examining of the patients) have a reduced capacity for answering to stimulation.

[Rationale for surgical treatment of focal liver diseases].

A 19-year experience with surgical treatment of the patients with focal hepatic lesions is presented. Hepatic resection was performed in 149 patients. Of them, 52 underwent atypical resection with the use of ultrasound aspirator, laser scalpel, temporary exclusion of the liver out of circulation, placement of staple suture of the parenchyma, preliminary roentgenovascular embolization of the major vessels of the lobe removed.