Probl Endokrinol (Mosk)
September 1989
Patients with primary chronic adrenal insufficiency (PCAI) in decompensation demonstrated a decrease in the total level of blood immunoglobulins, in particular IgG, with the normal level of B-lymphocytes. A decrease in IgG and an increase in IgA content was noted in the eucorticoid state; relative and absolute lymphocytosis determined by an increase in T- and B-lymphocytes was also noted. In overdosage of cortisone acetate the total number of immunoglobulins was normal, but IgA was raised and IgG lowered.
View Article and Find Full Text PDFExamination of 13 untreated patients with Itsenko--Cushing disease and syndrome showed an increase in total Ig as well as IgA, IgM and IgG, a decrease in the number of O-cells, and the absence of significant change in in the blood content of T-lymphocytes. A decrease in the amount of B-lymphocytes was noted in this group of patients with GTT of diabetic type or mild diabetes mellitus. Repeated examination of 7 of these patients 1-1.
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