Morphological characteristics of the lung are presented for rats and hamsters with esophageal and lung damages following chest exposure to 10-100 Gy. A four-month post-exposure follow-up revealed changes in the lung tissue in all cases. Depending on radiation dose, lung damages differed in genesis and time of development.
View Article and Find Full Text PDFIn experiments with 933 (CBA x C57Bl)F1 mice it has been found that with any variant of alternation and sequence of single ionizing and SHF irradiation with lethal doses, the radiation affection caused by gamma quanta is aggravated. Preirradiation with gamma or SHF radiation ameliorates the severity of the affection caused by the subsequent SHF radiation. Parenteral injection of colloidal sulfur 60 min before SHF radiation causes a 2-5-fold increase in the survival rate of exposed and protected mice as compared to unprotected animals.
View Article and Find Full Text PDFArkh Anat Gistol Embriol
January 1986
By means of mark scale estimation method, discriminant and factor analyses, changes in integral indices on the state of mast cells in the rat mesentery have been investigated in dynamics of medullary, intestinal and cerebral forms of an acute radiation sickness. The integral indices are calculated basing on the morphometric parameters of the cells, that are obtained after the histological preparations are treated in a special automatic system for analysing images. At the medullary form of the acute radiation sickness, the greatest structural rearrangements of the mast cells take place during the first hours after the radiation, as well as during the climax of the disease, at the intestinal form, the analogous changes are revealed 1-3 days after the effect, and at the cerebral form--3 h after the radiation.
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