Based on results of 15-years complex study, the authors present toxicological and hygienic characteristics of terpene compounds (with mono- and bicyclic structure) and their compositions. The article deals with toxicodynamics and toxicokinetics of terpenoids, dependence of toxic properties on the chemical structure. The article also touches upon studies of biologic and specific (sensibilizing activity, embryotoxic and gonadotropic, membranotropic) effects of terpenoids.
View Article and Find Full Text PDFMed Tr Prom Ekol
April 2001
The authors defined major criteria for allergenic danger caused by work conditions. The criteria include sensibilizing activity, intensity of chemical allergen, routes of its intake, combinations and associations with other occupational hazards and, according to hygienic classification of work and to classification of chemical allergens, to importance in causing the allergic diseases, are assessed in points. Using the criteria, considering various associations of allergies and concomitant factors and their correspondence to occurrence and severity of immunologic and allergic disorders, clinical signs of allergies (including occupational), the authors specified integral scale for evaluation of allergenic danger caused by work conditions.
View Article and Find Full Text PDFThe maximum permissible concentrations (MPC) of Viterol in water were established, which was equal to 0.14 mg/l. Its organoleptic and general sanitary thresholds were determined at the same level.
View Article and Find Full Text PDFThe MACs for aerosols of low-soluble lead compounds should be 10 times higher than those for inorganic lead compounds.
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