[Hemostasis and lipid peroxidation in the therapy of brain concussion at exacerbation].

130 patients with brain concussion (BC) and 30 virtually healthy subjects, aged 16 to 50, were examined for the purpose of studying the influence exerted by different drugs affecting blood coagulation, fibrinolysis, lipid peroxidation (LPO) and antioxidant protection at exacerbation. Changes of hemostasis in BC were shown to be of the adaptation nature and to depend essentially on a conducted treatment. Normalized plasma components in the hemostasis system were registered in groups receiving cavinton.

[Ways to decrease blood loss during total hip joint endoprosthesis].

Total replacement (endoprosthesis) of the hip joint was carried out in 93 patients aged 18-60 years. Sixteen operations were performed under prolonged epidural blockade, 66 under neuroleptanalgesia, and 16 under ataralgesia. A deficiency of circulating blood volume was detected in all patients before surgery.

[The correction of the disseminated intravascular coagulation syndrome in the emergency surgery of gastrointestinal tract cancer].

The authors estimate results of correction of the hemostasis system in surgical treatment of 63 patients with complicated carcinoma of the gastro-intestinal tract. It was found that purulent peritonitis, profuse hemorrhage and obturative obstruction facilitated the development of local and generalized DIC syndrome. Methods of correction of the hemostasis system, endogenous intoxication during preoperative preparing are described.

[The intensive therapy of posthypoxic encephalopathy].

A complex of therapeutic measures including hyperbaric oxygenation combined with heparin and endolumbal injection of glucocorticoids, proteolysis inhibitors, was carried out in 49 patients aged 16 to 95 with posthypoxic encephalopathy caused by mechanical asphyxia (11 patients,) carbon monoxide (12 cases), narcotics (18 cases), and closed craniocerebral injury (8 patients). Lipid peroxidation, some parameters of homeostasis, electrolyte, acid-base, and gaseous composition of the blood and liquor were studied before and during treatment. Positive clinical results were attained in 88.

[The diagnosis and clinical assessment of the disseminated intravascular coagulation syndrome in complicated cancer of the gastrointestinal tract].

Under study were the state of the hemostasis system, the level of endogenous intoxication and anti-infectional defense in 63 patients with complicated carcinoma of the gastro-intestinal tract (GIT). It was established that the patients had the syndrome of disseminated intravascular coagulation (DIC) of blood which at first was of local character. Acute complications of carcinoma of GIT, first of all purulent peritonitis and profuse gastro-intestinal bleedings, aggravate endotoxicosis and facilitate the development of the acute DIC syndrome.