[Decontamination of freshly caught fish infected with Opisthorchis metacercariae by fast electron irradiation].

An experiment that decontaminated of opistorchide metacercariae-infected fish is described. Decontamination was accomplished by fast electron radiation on an ILU-6 accelerator. A high larval mortality (about 98-100%) was shown in the biological control invasions of the experiment animals exposed to radiation in different doses from 1.

[Cellular mechanisms of calcium regulation of cardiac rhythm in children with ectopic arrhythmias].

Regulation of intracellular calcium homeostasis by means of secondary mediators calmodulin and 4,5-inositol phosphates (products of phosphatidyl inositol hydrolysis) was studied in children with ectopic forms of arrhythmias. Alterations in the system calmodulin-Ca2+ and the activity of phosphoinosite metabolism correlated highly with clinical manifestations of the arrhythmias. The data obtained suggest that a number of molecular mechanisms and responsible for arrhythmias were realized in cell membranes and depended on a complex of intracellular messengers affected within various steps of the hormonal signal transmission.

[Disorders of membrane mechanisms for regulating calcium homeostasis in cardiac arrhythmias in children].

Importance of calmodulin and Ca2+ in membranes of erythrocytes and myocardium was studied in children with ectopic forms of cardiac arrhythmia--extrasystole, paroxysmal and nonparoxysmal tachycardia. Activation of lipid peroxidation and shifts in cytomembrane phospholipid spectrum were shown to be involved in impairments of calcium homeostasis regulation, which is responsible for control of electromechanical parameters and may be related to deterioration of myocardial electrophysiological properties.