[Therapy of asthenic disorders after psychotic conditions in patients with cognitive impairment: results of an observational non-interventional program].

Objective: An observational non-interventional study was conducted to obtain data on the efficacy and safety of Prospekta in the treatment of postpsychotic asthenia in patients with cognitive impairment (CI).

Material And Methods: We selected 69 patients aged 18-75 years with asthenic disorders that developed after suffering psychotic conditions and CI, who were prescribed Prospekta. At four visits (at baseline, after 2, 4 and 8 weeks), the doctor collected complaints, anamnesis, examined the patient, assessed the severity of asthenia on the MFI-20 (The Multidimensional Fatigue Inventory-20) scale, CI - on the MMSE (The Mini-mental state examination).

[Cardiac rhythm disorders and arterial hypertension in treatment-compliant patients with alcoholic dependence: features of the clinical course and therapy].

Features of dynamics of arterial hypertension and rhythm disorders within 3 years after the termination of alcohol intake were studied. The study included 260 patients with alcoholic dependence at the age from 22 to 74 years (mean age 46±6.6 years).

[The risk of sudden cardiac death in patients with alcohol addiction: how urgent is a problem?].

Features and variants of cardiovascular pathology among patients with alcohol addiction were analyzed in 251 patients with II-III degrees of alcohol addiction during 3 years. Treatment and compliancy of patients were taken into account. Based on the results of the primary clinical and instrumental examination, patients were divided into two groups depending on the presence (181 patients) or the absence (70 patients) of cardiovascular pathology.

[Mental disorders following delirium tremens].

Twenty-four patients, aged between 29-62 years (average age - 44+/-11 years), at the post-psychosis period of delirium tremens were observed. In 19 patients, this period was characterized by a triad of mental disorders including cognitive dysfunction, affective disturbances and alcohol anosognosia. Memantine was recommended for all patients with mental disorders.