An activator of phosphoprotein phosphatase from bovine spleen cell nuclei has been isolated from different tissues (rat liver, bovine liver, spleen and kidney). The activator increases the enzyme activity by a factor of 4-5. The activator is heat-stable (it withstands incubation at 95 degrees C for 10 min) but loses its activity by 50% in 6-7 hrs at 4 degrees C.
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