[Use of allicor to lower the risk of myocardial infarction].

The aim of the study was to investigate the effects of allicor (a long-action garlic-based preparation) on the risk of acute myocardial infarction (MI) and sudden death (SD) in patients with coronary artery disease (CAD). Fifty one CAD patients were included in this double-blind placebo-controlled study. The prognostic risk of MI and SD during ten following years was counted using Cox proportional hazards model based on the results of Munster study.

[Allicor efficacy in lowering the risk of ischemic heart disease in primary prophylaxis].

Aim: To assess effects of allicor (a long-acting garlic drug) on the risk of ischemic heart disease (IHD) in primary prophylaxis of cardiovascular diseases.

Material And Methods: A double blind placebo-controlled study investigated for a year changes in multifactorial risks of cardiovascular events or their complications in 167 patients with hyperlipidemia free of IHD.

Results: In men, intake of allicor for 12 months resulted in a 10.

[Reduction of cardiovascular risk in primary prophylaxy of coronary heart disease].

The purpose of the study was to evaluate the effects of Allicor, an Allium sativum (garlic) preparation with prolonged activity, on 10-year prognostic risk of coronary heart disease (CHD), acute myocardial infarction (MI) and sudden death in patients with elevated and high risk of CHD. 79 patients with elevated and high risk of CHD were included in a double blind randomized placebo-controlled study. They underwent multifactor evaluation of cardiovascular risk by algorithms based on the results of Framingham and Munster studies.

[A comparative evaluation of treatment methods for a genital papillomavirus infection in women with different viral genotypes].

Such genotypes of human papilloma virus (HPV) as "malignant" (180), "benign" (49) and indeterminate (127) were identified in 356 females by PCR and cytological procedures. The following therapeutic techniques were compared: cryodestruction of the uterine cervix (60), antiviral medication (AVM) (19), combination of AVM and cryodestruction (224), and combination of AVM and laser destruction (54). In the "malignant" HPV group, AVM in conjunction with cryo- or laser destruction was significantly more effective than cryodestruction or AVM alone.

[Human oncogene expression in the normal state and in various blood system diseases].

A study was made of the expression of the cellular oncogens c--myc, c--sis and c--abl in mononuclears from normal donors and patients with different patterns of leukemia and hemopoietic dysplasia using spot hybridization on nitrocellulose filters with virus homologs of the given oncogens. Altogether 43 persons were examined. No specific expression of the oncogens indicated was established whatever the pattern of leukemia.