Unlabelled: Appearance of a thrombus in the graft intraoperatively during Fontan surgery is not reported and warrants careful evaluation. Our patient was an 18-year-old lady who underwent fenestrated extracardiac Fontan surgery. Intraoperatively, transesophageal echocardiography revealed an echogenic structure inside the conduit.
View Article and Find Full Text PDFPurpose: In adult studies, MRI volumetrics is a proven technique in presurgical assessment of epilepsy. Hippocampal volume loss is maximal in the syndrome of mesial temporal lobe epilepsy. We aimed (a) to validate this methodology in a pediatric outpatient epilepsy population (b) to determine the relationship of hippocampal asymmetry (HA) to epileptic syndromes and risk factors.
View Article and Find Full Text PDFBackground: Children with solid tumors that progress or recur after conventional multimodality therapies have a very poor prognosis. In a pilot study, vincristine, etoposide, and dose-escalated cyclophosphamide (VETOPEC) was shown to be a promising salvage regimen. Continued accrual of patients and increased duration of follow-up has resulted in substantial experience with VETOPEC.
View Article and Find Full Text PDFChronic recurrent multifocal osteomyelitis (CRMO) is an extremely rare condition, of uncertain aetiology. Since first described, in 1972, under 100 cases have been reported. It is being reported with increasing frequency, and many cases of this disease go unreported.
View Article and Find Full Text PDF1. Currently available pharmacological therapies treat arthritis inadequately. We have previously found that the kappa (kappa)-opioid, U-50,488H (trans-(+/-)- 3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl) cyclohexyl]- benzene-acetamide methane sulphonate), possesses anti-arthritic effects.
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