[Influence of non-opiate analgesia on postoperative pain intensity and patient satisfaction].

Objective: To compare the results of postoperative opiate and non-opiate analgesia.

Material And Methods: The study was carried out as a part of the OPERAS global trial. Analysis was conducted in accordance with the STROBE reporting guidelines for observational studies.

[Morphological and functional changes of organs of female and male reproductive systems at change of sex].

The aim of the study was to identify the effects of virilizing and feminizing hormone replacement therapy on the morphology and function of the male and female reproductive systems in the application of technology for change of sex. The results of the pathomorphorogic examination of the uterus with appendages, testes, the corpora cavernosa, and biopsies of the prostate and mammary glands at different times of treatment in transsexual patients aged from 22 to 43 years are presented. It was found that prolonged exposure to high concentrations of exogenous hormones in the women and men significantly increases the risk of tumors and tumor-like processes, such as endocervicosis, cervical intraepithelial neoplasia, metaplasia of the endometrium, endocervical and endometrial polyps, endometrial hyperplasia, proliferative processes in tubular epithelium, ovarian polycystic disease, mammary tumors, hyperplasia and metaplasia of the ductal epithelium of the prostate gland.

[Vaginoplasty with inverted penile skin in male-to-female sex reassignment surgery].

The article presents the results of vaginoplasty in male-to-female sex reassignment surgery, technique of this operation, complications, long-term consequences, functional and social changes.

[Efficacy of tadenan in chronic prostatitis complicated by sterility].

Efficacy of tadenan was studied in combined treatment of 30 patients suffering from chronic prostatitis complicated by sterility. Positive results were achieved. Tadenan efficacy manifested with attenuation of the symptoms, improvement of spermogram, quality of life, prostatic structure, circulation, increased maximal urine flow rate.