[The results of the multicenter pharmaco-epidemiological observational project on the use of mydocalm in the treatment of pain syndromes with the muscle spasm].

The prospective multicenter open noncomparative pharmaco-epidemiological observational project on the use of mydocalm in real clinical practice has been completed in 2013. The project has been performed in 2090 clinical/rehabilitation settings in 284 cities of 13 countries using the results of 35,383 patients. The project aimed to assess the safety of treatment (percentage of patients with adverse-effects) and pain relieving efficacy as well as patient's satisfaction with the treatment.

[Medical, psychological, social and gender aspects of aging in modern Russia].

In this article, the authors considered controversial issues ambiguous attitude to the aging process of the population of the Russian Federation on the basis of a number of individual differences--psychological, social, sexual, and medical. The thesis is that, unfortunately, the fight against aging appears rather to be more a struggle with an already existing old age, and you need to develop preventive measures against aging much earlier than is currently done. Submissions own research confirm this position.

[Comparative biochemistry of process of ageing in men and women].

In the research of a number of biochemical indicators in 858 men and 899 women aged from 20 till 70 years divided into 6 compared groups depending on age and gender clear distinctions in the dynamics of the components of the lipid status, status of lipid peroxidation and antioxidant activity of the blood system, the content of middlemolecular peptides are revealed. Simultaneous determination of the biological age of the subjects also revealed a distinct gender differencies testifying to lower rate of aging of men, despite the probability of earlier, in comparison with women, development of dislipidemia and atherosclerosis. Association of the received gender distinctions both with changes of level of estrogen in women due to menopause and with the peculiarities of stressful impacts on male and female organism in different age periods is supposed.

[Depressive disorders in elderly and senile patients in the period of rehabilitation after acute ischemic stroke].

To definite the probability of occurrence of depression after suffering an ischemic stroke in elderly and senile age and the impact of depressive disorders on the results of the rehabilitation treatment the comparative study of 186 patients aged over 70 and 110 patients at the age of 33-60 years was carried out. The results testify that the frequency of occurrence and severity of post-stroke depression do not depend on age. But the depression has a more significant impact on the results of the rehabilitation treatment in the elderly than in patients of the young and middle age, which is explained by a long existence in the period prior to the stroke of the emotional-volitional disorders, characteristic for the elderly and senile age.

[Treatment of elderly and senile patients suffering from benign prostatic hyperplasia and chronic prostatitis].

In the clinical settings and in animal experiments the research was conducted on effectiveness and safety of treatment the benign prostatic hyperplasia, chronic prostatitis in the stage of active inflammation in elderly and senile patients. The method of treatment including transrectal fonoforez of the Russian preparation of Tisol (Tisolium, gel, the company "Olympus" Yekaterinburg) in combination with diclofenac sodium protected by patents of the Russian Federation was used. The developed method of treatment has shown high efficiency and safety, which is confirmed by experimental, clinical, laboratory and instrumental studies.