Anti-viral and Anti-inflammatory Isoflavonoids from Ukrainian Iris aphylla Rhizomes: Structure-Activity Relationship Coupled with ChemGPS-NP Analysis.

Dried rhizomes have been used in Chinese and European traditional medicine for the treatment of various diseases such as bacterial infections, cancer, and inflammation, as well as for being astringent, laxative, and diuretic agents. Eighteen phenolic compounds including some rare secondary metabolites, such as irisolidone, kikkalidone, irigenin, irisolone, germanaism B, kaempferol, and xanthone mangiferin, were isolated for the first time from rhizomes. The hydroethanolic extract and some of its isolated constituents showed protective effects against influenza H1N1 and enterovirus D68 and anti-inflammatory activity in human neutrophils.

Effect of ecological factors on the accumulation of phenolic compounds in Iris species from Latvia, Lithuania and Ukraine.

Introduction: It is important to conduct studies on the influence of environmental factors on the accumulation of secondary metabolites in plants, as well as the cultivation of plants and harvesting of their raw material.

Objective: In this study, we examined the influence of habitat types, soil composition, climatic factors and altitude on the content of phenolic compounds in Iris species from different populations in Latvia, Lithuania and Ukraine.

Methodology: According to high-performance liquid chromatography (HPLC) analysis, 25 compounds (flavonoids, isoflavonoids, isoflavonoid glucosides, xanthones, phenolcarboxylic acids) were identified in the methanol extracts of 16 samples of Iris rhizomes.

Biologically active compounds and pharmacological activities of species of the genus Crocus: A review.

The present article is the first comprehensive review on the chemical composition and pharmacological activities of the raw materials of Crocus species. In the present review, data on chemical constituents and pharmacological profile of Crocus sativus stigmas, as well as of other plant parts (perianth, stamens, leaves, corms) of different Crocus spp. are given.

Fatty acid composition of lipids of Iris sibirica.

Different Iris species are a rich source of secondary metabolites and they are widely used due to their medicinal properties, i.e. such as antibacterial, cytotoxic, hepatoprotective, antiplasmodial, and immunomodulatory effects.

Gas chromatography - mass spectrometry studies of the component composition of carboxylic acids of the rhizomes of Iris medwedewii and Iris carthaliniae (Iridaceae).

The composition of carboxylic acids of the rhizomes of Iris carthaliniae and Iris medwedewii by the gas chromatography - mass spectrometry method has been studied for the first time. The total content of carboxylic acids for I. carthaliniae was 1.