[Plasmid spectra and phagotypes of Escherichia coli strains isolated from patients with large intestine tumours].

The work deals with connection between plasmid spectra and phagotypes of Escherichia coli strains isolated from patients with tumours in large intestine. It has been established that 70 % of this bacterium isolates from the normal tissue, intestine lumen and tumours are characterized by multiple content of plasmids. Sometimes large endogenic plasmids are accompanied by the closed ring DNA with discrete sizes: 3.

[Mu-induced deletions and mutations of Erwinia carotovora chromosomes, including resident prophages E105 and 59].

The plasmid RP4::Mu cts62 in stably inherited by Erwinia carotovora 268 strain. Under the conditions of thermoinduction bacteriophage Mu is segregated and completely eliminated more intensively than in Escherichia coli cells. At thermoinduction the transposition of bacteriophage Mu cts62 into different chromosomal sites takes place, causing the induction of chlorate resistant and auxotrophic mutants with the frequency of 10(-4).

[Erwinia carotovora as a recipient system for the natural hybrid plasmid RP4::Mu cts62].

The plasmid RP4::Mu cts62 is transferred from Escherichia coli cells into a recipient strain Erwinia carotovora 268 by conjugation with the frequency 1.5-5 x 10(-7) per donor cell. The maximal frequencies of transfer are obtained by cultivation of donor and recipient cells for 3-5 h on the filters.

[The multiple effect of plasmid RP4::Mu cts 62 in transcipient bacilli].

Transfer of conjugative hybrid plasmid RP4::Mu cts 62 from Escherichia coli into Bac. cereus, Bac. thuringiensis, Bac.

[The infection of bacilli by Mu cts phage integrated into the plasmid].

The infection of Bacillus thuringiensis, B. cereus, B. mesentericus and B.