No association between genetic markers and hypertension control in multiple cross-sectional studies.

We aimed to assess whether genetic markers are associated with hypertension control using two cross-sectional surveys conducted in Lausanne, Switzerland. Management of hypertension was assessed as per ESC guidelines using the 140/90 or the 130/80 mm Hg thresholds. One genetic risk score (GRS) for hypertension (18 SNPs) and 133 individual SNPs related to response to specific antihypertensive drugs were tested.

Trends and determinants of prevalence, awareness, treatment and control of dyslipidaemia in canton of Geneva, 2005-2019: Potent statins are underused.

We assessed 1) trends in prevalence, awareness, treatment and control rates of dyslipidaemia and associated factors, 2) the effect of statin generation/potency on control levels and 3) the effect of ESC lipid guidelines, on lipid management. Data from multiple cross-sectional, population-based surveys conducted between 2005 and 2019 in the canton of Geneva, Switzerland, were used. Prevalence, awareness, treatment and control rates of dyslipidaemia were 46.

Association of clinical and genetic risk factors with management of dyslipidaemia: analysis of repeated cross-sectional studies in the general population of Lausanne, Switzerland.

Objectives: To assess the importance of clinical and genetic factors in management of dyslipidaemia in the general population.

Design: Repeated cross-sectional studies (2003-2006; 2009-2012 and 2014-2017) from a population-based cohort.

Setting: Single centre in Lausanne, Switzerland.

Association between genetic risk of high SBP and hypertension control: the CoLaus|PsyColaus study.

Objective: To assess whether a genetic risk score (GRS) for high SBP is associated with poor control of hypertension.

Methods: Data from the four waves of a population-based, prospective study conducted in Lausanne, Switzerland. Control of hypertension was defined based on SBP less than 140 mmHg and DBP less than 90 mmHg.

The relation between cryoprotective and physicochemical properties of oxyethylated methyl cellosolve-based media.

Oxyethyl derivatives of polyol class members such as glycerol and ethylene glycol with various polymerization degrees possess low toxicity and cryoprotective properties via an exocellular mechanism. To develop the cryoprotective media based on non-penetrating cryoprotectants, we studied cryoprotective and physico-chemical properties of oxyethylated methyl cellosolve (OEMC)-based media. Media containing 20% and 30% OEMC were prepared with 50 mmol/l and 150 mmol/l NaCl.