[Extracorporeal methods of hemocorrection in the combined treatment of patients with purulent surgical infection of soft tissues complicated by sepsis].

Extracorporeal methods of hemosorption and detoxication were used in treatment of 293 patients with purulent surgical infection of soft tissues complicated by sepsis. In 35 patients with the same nosology the methods in question were not employed. An analysis of the clinical observations has shown that lethality in the main group was reduced to 23.

[Optimization of indirect electrochemical detoxication in the treatment of different endogenous intoxications and multiple organ failure syndrome in resuscitation practice].

The authors have made a statistical analysis of clinical groups of patients in the units of resuscitation and intensive therapy of a general profile and of the archive materials of a laboratory of extracorporeal hemocorrection. The ultraviolet and laser photomodification of autoblood, hemosorption, plasmapheresis, ultra- and hemofiltration were used in the complex treatment of these patients. In the experimental group there were 190 patients on whom 333 operations of extracorporeal hemocorrection were made with using indirect electrochemical detoxication (IECD).

[Effects of extracorporeal hemo-correction on lipid peroxidation in patients in critical states].

The article presents an analysis of immediate influence of extracorporeal hemocorrection upon the indices of lipid peroxidation in resuscitation patients of a surgical profile. It was found that hemosorption, ultrafiltration and their combination exert a moderate detoxicating effect on lipid peroxidation products. The detoxicating effect of plasmapheresis is negligible.

[Extracorporeal hemocorrection in acute pancreatitis].

An experience with using 340 operations of extracorporeal hemocorrection in complex intensive therapy of 160 patients with acute pancreatitis has been generalized. In 111 of these patients (69%) pancreatic necrosis complicated by the syndrome of multiple organ failure was diagnosed. Based on the mechanisms of medical efficiency the authors have developed differential indications for using different extracorporeal technologies depending on the clinico-laboratory profile of the endogenous intoxication, structure and degree of organic and systemic dysfunctions.

[Classification of acute dysfunctions of organs and systems in multiple organ failure syndrome].

A classification of acute dysfunctions of the vital organs and systems in cases with multiple organ failure is proposed. It is suggested to assess the function as satisfactory, compensatory sufficiency, decompensated insufficiency, or failure. Clinical laboratory criteria of such rating are offered.