[Effect of one-time and chronic low-intensity irradiation on cathepsin L activity in rat brain].

The effect of the total single and chronic roentgen irradiation in the dose of 0.25 Gy on the rats to alteration dynamics in lysosomal cysteine cathepsin L [CE 3.4.

[Cathepsin L from human brain tumor. Purification and contents].

Cysteine cathepsin L was isolated and purified 1242-fold from human brain. Cathepsin L pH-optimum, Vmax, K(m), lysosomal origin and thiol nature were determined. The distribution of cathepsin L activity in human brain tumours of different histological structure, histogenesis and degree of malignization was studied.

[Organization and development of neurochemical research in the Dnepr area (the 60-80s)].

The development of neurochemical investigations at the Institute of Biochemistry of the National Academy of Sciences of Ukraine initiated by Academician A. V. Palladin, has impelled specialists in some regions of the country to start research in this trend.

[The effect of x-ray radiation and hypoxia on the proteolytic activity of the normal rat spleen and during tumor growth].

The influence of X-radiation on activity of lysosomal enzymes (D, L, H cathepsins) in rat spleen tissue and in inoculated rat sarcoma 45 has been investigated. Intact rats and rats with tumors were subjected to whole-body and sarcoma 45 to local irradiation with doses of 0.155 C/kg and 0.

[Clinico-biological evaluation of the status of newborn infants and the tactics in the management of the early postnatal period].

Biology of the perinatal period as a basis of neonatal management is an area of conceptual controversy. Literature evidence and findings of a clinical and functional study in 175 term newborns support the concept of intrapartum and neonatal stress. This is a rationale for a strategy of maintaining the adaptive mechanisms of the fetus and newborn in a maximal range and active support of neonatal homeostasis.