The relevance of the study is expressed by the improvement and development of tools for managing social processes and public procedures. There are a large number of concepts and theories that explain certain aspects of public opinion: exposure to influence, an impact on people's actions, and its contradictory nature. The main forming factors of individual behavior are the stereotypes and values that are developed within society.
View Article and Find Full Text PDFA green, scalable, and sustainable approach to prepare aqueous fullerene dispersions (AFD) C, C, endohedral metallofullerene Gd@C, and their derivatives CCl, CCl, and supramolecular and ester-like derivatives, 10 fullerene species total, is proposed. For the first time, an immersed ultrasonic probe was used to preparing dispersions for pristine fullerenes without addends. Both ultrasound-assisted solvent-exchange and direct sonication techniques for AFD preparation using an immersed probe were tested.
View Article and Find Full Text PDFUnlabelled: The hyperplastic processes of the endometrium can arise not only against the background of excessive influence of estrogen, but also against the background of epigenetic damages that affect apoptosis, cell proliferation, differentiation, and adhesion, and DNA reparation. The aim of our study was to investigate and analyze the status of methylation of the promoter of SFRP2 gene in patients with hyperplastic processes of the endometrium.
Materials And Methods: The study groups were the following: I - patients with endometrial hyperplasia (EH, n = 9); II - patients with endometrial intraepithelial neoplasia (EIN, n = 10), III - control groups: 1) with endometrial cancer (EC, n = 4), and 2) healthy women (n = 4).
Identification of a single molecular trait that is determinant of common malignancies may serve as a powerful diagnostic supplement to cancer type-specific markers. Here, we report a DNA methylation mark that is characteristic of seven studied malignancies, namely cancers of lung, breast, prostate, pancreas, colorectum, glioblastoma and B cell chronic lymphocytic leukaemia (CLL) (n = 137). This mark was defined by substantial hypermethylation at the promoter and first exon of growth hormone secretagouge receptor (GHSR) through bisulfite pyrosequencing.
View Article and Find Full Text PDFWe show that electron transfer from the perchlorotriphenylmethide anion (PTM(-)) to Y@C82(C2v) is an instantaneous process, suggesting potential applications for using PTM(-) to perform redox titrations of numerous endohedral metallofullerenes. The first representative of a Y@C82-based salt containing the complex cation was prepared by treating Y@C82(C2v) with the [K(+)([18]crown-6)]PTM(-) salt. The synthesis developed involves the use of the [K(+)([18]crown-6)]PTM(-) salt as a provider of both a complex cation and an electron-donating anion that is able to reduce Y@C82 C2v).
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