Human neural dynamics of real-world and imagined navigation.

The ability to form episodic memories and later imagine them is integral to the human experience, influencing our recollection of the past and envisioning of the future. While rodent studies suggest the medial temporal lobe, especially the hippocampus, is involved in these functions, its role in human imagination remains uncertain. In human participants, imaginations can be explicitly instructed and reported.

Influences of electrode density on intracranial seizure localisation: a single-blinded randomised crossover study.

Background: Successful seizure onset zone (SOZ) localisation for epilepsy surgery often relies upon intracranial recordings. Accurate delineation requires anatomical detail yet influences of intracranial electrode density on clinical variables have not been systematically studied.

Methods: In this experimental study we compared SOZ localisation between spontaneously captured seizures on higher-density depth and grid electrode arrays (4-5 mm inter-electrode spacing) vs.

Relationship between Systolic Ejection Time and Inflammation in End-Stage Heart Failure.

Objectives: Systolic ejection time (SET) and systemic inflammation are two essential indicators of heart failure (HF) progression. We aimed to evaluate the associations between SET and inflammatory mediators in end-stage HF.

Methods: Participants included 16 patients with end-stage HF recruited from the Heart Failure Clinic at Toronto General Hospital and 16 healthy individuals free of any known cardiovascular disease.

Significance, applications, and contributions of Gamma Knife radiosurgery in advancing neurosurgical care in lower-middle-income countries: a systematic review.

Objective: Gamma Knife radiosurgery (GKRS) is an important neurosurgical intervention most commonly used for pathologies such as meningiomas, acoustic neuromas, paragangliomas, arteriovenous malformations, and trigeminal neuralgia. While the widespread availability of GKRS in developed countries makes it ubiquitous in neurosurgical research, there is a huge disparity in research in lower-middle-income countries (LMICs). This study aimed to quantify research undertaken by authors in LMICs on GKRS.

Comparative evaluation of red and white aril genotypes of Manila tamarind for fruit physicochemical and bioactive attributes.

The cultivation and trade of underutilized fruits are gaining prominence worldwide, largely on account of their capacity to contribute to a nutritious diet. Manila tamarind [Pithecellobium dulce (Roxb.) Benth] is a fast-growing, nitrogen-fixing tree, with a fairly high tolerance to abiotic stresses.