Migration routes and adult survival of the critically endangered yellow-breasted bunting Emberiza aureola.

Migratory animals rely on multiple sites during their annual cycles. Deteriorating conditions at any site can have population-level consequences, with long-distance migrants seen as especially susceptible to such changes. Reduced adult survival caused by persecution at non-breeding sites has been suggested a major reason for the catastrophic decline of a formerly abundant, long-distance migratory songbird, the Yellow-breasted Bunting Emberiza aureola.

[Prevalence of diabetic retinopathy assessed using two-field mydriatic fundus photography].

Unlabelled: Early detection of diabetic retinopathy (DR) is an urgent ophthalmological problem in Russia and globally.

Purpose: This study assesses the prevalence of asymptomatic retinopathy and attempts to identify risk groups for its development in patients with type 1 and 2 diabetes mellitus (T1DM and T2DM).

Material And Methods: The study involved clinics from 5 cities in the Russian Federation and it included 367 patients with DM, 34.

Antithrombotic Activity of a Novel Diazepino[1,2-α] Benzimidazole Derivative on Arterial Thrombosis Model in Rats without Concomitant Pathology and in Rats with Experimental Myocardial Infarction.

Antithrombotic activity of a novel tricyclic derivative of diazepino[1,2-α]benzimidazole (DAB-15) was examined on the model of arterial thrombosis developed in rats without concomitant pathology and in rats with experimental myocardial infarction. DAB-15 demonstrated high antithrombotic efficacy in modeled thrombosis of carotid artery in rats without the concomitant pathology surpassing that of the reference drugs acetylsalicylic acid and clopidogrel by 5.1 and 4.

Intraocular pressure-lowering effects of imidazo[1,2-a]- and pyrimido[1,2-a]benzimidazole compounds in rats with dexamethasone-induced ocular hypertension.

Ocular hypertension is believed to be involved in the etiology of primary open-angle glaucoma. Although many pharmaceutical agents have been shown to be effective for the reduction of intraocular pressure (IOP), a significant opportunity to improve glaucoma treatments remains. Thus, the aims of the present study were: (1) to evaluate the IOP-lowering effect of four compounds RU-551, RU-555, RU-839 (pyrimido[1,2-a]benzimidazole), and RU-615 (imidazo[1,2-a]benzimidazole) on steroid-induced ocular hypertension in rats after single drop and chronic applications; and (2) to test in silico and in vitro conventional rho-associated kinase (ROCK) inhibitory activity of the selected compound.

[The Problem of Adherence to Therapy in Cardiology].

This review article presents results of studies on adherence to drug therapy of patients after discharge from hospital. It contains analysis of the reasons for poor adherence, assessment of the impact of quality of adherence on the immediate and long-term results of surgical and medical treatment, structured methods of improvement of adherence to therapy; as well as economic aspects of the problem.