Publications by authors named "V V Al'fonsov"

[Biological effects of thrombin].

Fiziol Zh SSSR Im I M Sechenova

January 1984

The influence of thrombin on functional and procoagulant activity of lymphocytes, monocytes, fibroblats and tumour cells, was studied. Thrombin enhanced phagocytic activity of monocytes and decreased the speed of their migration from the center of inflammation, accelerated growth of fibroblasts and tumour cells and increased synthesis of oxyprolin and glycosaminglycans by fibroblasts. Thrombin activated functional activity of cells, increased their procoagulant and fibrinolytic activity with the release of thromboplastic agents, plasminogen activator and plasmine-like enzyme.

View Article and Find Full Text PDF

The study was concerned with the effect of thrombin and Xa-factor on the procoagulative and fibrinolytic properties of cultured malignant cells (Hep-2). It was found that active coagulative factors of the blood promote the procoagulative and fibrinolytic potential of neoplasms involving the release of thromboplastic compounds and plasminogen activator into the environment.

View Article and Find Full Text PDF