Training, networking, and support infrastructure for ombudspersons for good research practice: A survey of the status quo in the Berlin research area.

Recent developments in the German academic landscape have seen a shifting approach to promoting research integrity. In 2019, the German Research Foundation (DFG) incentivized all research and higher education institutions to appoint ombudspersons who advise members of their institution in matters of good research practice or suspected research misconduct. These ombudspersons for good research practice, usually professors who act in this function on a voluntary basis, need institutional support to be prepared for and fulfill their diverse duties.

Cytokeratin 13 (CK13) expression in cancer: a tissue microarray study on 10,439 tumors.

Cytokeratin 13 (CK13) is a type I acidic low molecular weight cytokeratin, which is mainly expressed in urothelium and in the squamous epithelium of various sites of origin. Loss of CK13 has been implicated in the development and progression of squamous epithelial neoplasms. To comprehensively determine CK13 expression in normal and neoplastic tissues, a tissue microarray containing 10,439 samples from 131 different tumor types and subtypes as well as 608 samples of 76 different normal tissue types was analyzed by immunohistochemistry.

In vitro comparison of two types of digital X-ray sensors for proximal caries detection validated by micro-computed tomography.

Objectives: We aimed to compare the diagnostic accuracy of two intraoral digital X-ray sensors-the charged-coupled device (CCD) and complementary metal-oxide-semiconductor (CMOS)-for proximal caries detection in permanent molar and premolar teeth. Micro-CT served as the reference standard.

Methods: 250 samples were mounted in three-dimensional (3D)-printed phantoms, and their proximal surfaces were evaluated by ICDAS criteria directly to create a balanced sample.

Radiosynoviorthesis of knees by means of 166Ho-holmium-boro-macroaggregates.

The aim of this study was to evaluate adverse and therapeutic effects of applicated holmium-boro-macroaggregates (HBMAs) in the radiosynoviorthesis (RSO) of knees in patients suffering from chronic synovitis. We started RSO of the knees by means of a new radiopharmaceutical (RF) HBMA in patients with gonarthrosis, rheumatoid arthritis, chronic synovitis, psoriatic arthritis, and gout arthropathy. Seventeen (17) intra-articular injections were performed in 15 patients who were receiving a mean activity of 972 MBq (range, 904-1057) of 166Ho-HBMA.