Publications by authors named "V Tobias"

Study Objectives: McLeod syndrome is a very rare multisystemic neurodegenerative disease linked to mutations in the gene. It has cardiac, neurologic, and neuromuscular manifestations and shares similarities with Huntington's disease. The aim of this study was to evaluate sleep patterns of patients affected by McLeod syndrome.

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Many estuarine ecosystems and the fish communities that inhabit them have undergone substantial changes in the past several decades, largely due to multiple interacting stressors that are often of anthropogenic origin. Few are more impactful than droughts, which are predicted to increase in both frequency and severity with climate change. In this study, we examined over five decades of fish monitoring data from the San Francisco Estuary, California, USA, to evaluate the resistance and resilience of fish communities to disturbance from prolonged drought events.

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Article Synopsis
  • The study investigates the effects of artificial gravity on red blood cells (RBC) during hypergravity exposure, specifically focusing on RBC deformability and aggregation, which are crucial for microcirculation.
  • Nine male subjects underwent two different hypergravity protocols using a centrifuge: one with a constant force and another with intervals of force and rest, with blood samples collected before and after the interventions.
  • Results showed that continuous artificial gravity increased RBC aggregation but did not significantly affect deformability or other blood parameters, suggesting that intermittent artificial gravity may be a better countermeasure for prolonged space flight.
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Glioblastoma multiforme (GBM) is a rare, highly aggressive brain tumor associated with a poor outcome in both children and adults. Treatment usually involves a combination of surgical resection, chemotherapy, and radiotherapy, but ultimately it is incurable. Evidence suggests that congenital GBM may have a better prognosis with improved survival compared with GBM in older children.

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The insect microsporidian Anncaliia algerae was first described in 2004 as a cause of fatal myositis in an immunosuppressed person from Pennsylvania, USA. Two cases were subsequently reported, and we detail 2 additional cases, including the only nonfatal case. We reviewed all 5 case histories with respect to clinical characteristics, diagnosis, and management and summarized organism life cycle and epidemiology.

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