Publications by authors named "V Thourani"
Objective: To compare outcomes of aortic valve replacement (AVR) in patients with pure aortic stenosis (Pure AS) and those with pure aortic regurgitation (Pure AR) or mixed AS and AR (MAVD) in the COMMENCE trial.
Methods: Of 689 patients who underwent AVR in the COMMENCE trial, patients with moderate or severe AR with or without AS (Pure AR + MAVD; n = 135) or Pure AS (n = 323) were included. Inverse probability of treatment weighting Kaplan-Meier survival curves were used for time-to-event endpoints, and longitudinal changes in hemodynamics were evaluated using mixed-effects models.
Article Synopsis
- The IMPACT SDM study evaluates the effectiveness of patient decision aids and clinician training in shared decision-making for severe aortic stenosis patients choosing between TAVR and SAVR.
- The study employs a hybrid effectiveness-implementation design across 8 US sites, surveying patients and clinicians to track the reach of decision aids and training adoption.
- It aims to identify barriers and facilitators to SDM implementation, providing insights for future efforts to enhance patient-centered care.