Publications by authors named "V Thom"
Background: Recently, cold atmospheric plasma (CAP), as well as adipose mesenchymal stem cells derived exosomes (ADMSCs-EX), have been applied separately to wound healing treatment. However, no study has investigated the additive effect on the healing mechanism of these two methods in the same skin lesion treatment model.
Aim: We conduct this study to describe the results of using CAP and human ADMSCs-EX on in vitro wound healing.
Factors related to unfavorable outcome in minor ischemic stroke.
J Stroke Cerebrovasc Dis
August 2023
Background: Stroke recurrence and disability are important challenges to overcome in patients with minor ischemic stroke. The aim of our study was to determine the factors associated with unfavorable outcomes in patients with minor ischemic stroke.
Methods: This was a prospective cohort study including patients with minor ischemic stroke with a National Institutes of Health Stroke Scale (NIHSS) score ≤ 4 who were treated at the Bach Mai Hospital stroke center from June 15, 2021, to September 15, 2022.
Article Synopsis
- Membrane chromatography is increasingly recognized as a more efficient method for purifying therapeutic proteins compared to traditional packed-bed column chromatography, mainly due to its higher productivity and lower buffer needs.
- This research introduces a novel high-throughput screening method using a 96-well plate format to efficiently test various membrane conditions for purifying monoclonal antibodies, which could shorten development times.
- The new screening technique improves mass transfer rates, resulting in faster and more effective optimization of the purification process while reducing the amount of feed material needed.
In biopharmaceutical process development time, cost and reliability are the relevant keywords. During the development of chromatographic processes these targets are challenged by many possible scaffolds, ligands and process parameters. The common response to this diversity is the establishment of platform processes in the development of chromatographic unit operations.
View Article and Find Full Text PDFExpansion of KPC-producing Enterobacterales in four large hospitals in Hanoi, Vietnam.
J Glob Antimicrob Resist
December 2021
Objectives: The incidence of carbapenem resistance among nosocomial Gram-negative bacteria in Vietnam is high and increasing, including among Enterobacterales. In this study, we assessed the presence of one of the main carbapenemase genes, bla, among carbapenem-resistant Enterobacterales (CRE) from four large hospitals in Hanoi, Vietnam, between 2010 and 2015, and described their key molecular characteristics.
Methods: KPC-producing Enterobacterales were detected using conventional PCR and were further analysed using S1 nuclease pulsed-field gel electrophoresis (S1-PFGE), Southern blotting and whole-genome sequencing (WGS) for sequence typing and genetic characterisation.