Publications by authors named "V Thohan"

Article Synopsis
  • Our understanding of how the atria (upper chambers of the heart) work and how they can become dysfunctional (atrial cardiomyopathy) has improved, especially regarding their impact on various heart conditions.
  • Different atrial medical procedures can affect the way the atria function, and it's important for healthcare professionals to be aware of potential negative effects that may not show up right away.
  • By identifying early signs of atrial dysfunction, clinicians can intervene sooner, potentially preventing serious changes in atrial structure and function before they lead to visible health issues.
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Article Synopsis
  • An interatrial shunt is being studied as a potential treatment for heart failure, aimed at lowering left atrial pressure and improving symptoms and outcomes for patients.
  • In a clinical trial involving 508 patients, participants were randomly assigned to receive either the shunt or a placebo, with their progress tracked over a maximum of two years.
  • Results showed that while the shunt had no major safety issues, it did not significantly improve overall effectiveness compared to the placebo, although it appeared to reduce adverse cardiovascular events in patients with reduced left ventricular ejection fraction.
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Article Synopsis
  • A study examined the use of the CardioMEMS pulmonary artery pressure sensor to manage chronic heart failure patients with left ventricular assist devices (LVADs), aiming to reduce hospitalizations.
  • The research involved 101 patients (52 with HeartMate II and 49 with HeartMate 3), tracking their pulmonary artery pressure, walking ability, quality of life, and hospitalization rates over six months.
  • Results showed that patients who significantly lowered their pulmonary artery diastolic pressure had better walking distances and fewer hospitalizations, indicating that the CardioMEMS system can effectively improve health outcomes in LVAD patients.
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Introduction: Heart failure hospitalization is a hallmark of disease progression associated with increased morbidity and mortality. Benefits of multidisciplinary clinics have been established in the care of heart failure patients and can be particularly impactful post-hospital discharge.

Objective: This study aimed to investigate the impact of a clinical pharmacist-integrated model of care within a Heart Failure Bridge Clinic (HFBC) at a large tertiary care referral center.

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Aims: Right ventricular (RV) allograft dysfunction is present in half of all heart transplant (HT) recipients. Non-invasive assessment of RV function in the setting of rejection is not well described. We outline an echocardiographic technique, short-axis fractional area change (SAXFAC), to evaluate RV function in the HT population and correlate this with the grade of pathologic rejection.

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