Survival outcomes following liver retransplantation (reSOFT) score: A model predicting survival after adult liver retransplantation.

Recipient and donor risk factors impacting adult liver retransplantation remain inadequately described in the modern era of liver transplantation. Our study aimed to develop a risk model for 3-month recipient survival following liver retransplantation using data from the Organ Procurement and Transplantation Network's (OPTN) liver transplantation database. We conducted univariate and multivariable analyses on 6,660 adult patients who underwent liver retransplantation between 2002 and 2023.

Variation in HIV-1 Tat activity is a key determinant in the establishment of latent infection.

Despite effective treatment, human immunodeficiency virus (HIV) persists in optimally treated people as a transcriptionally silent provirus. Latently infected cells evade the immune system and the harmful effects of the virus, thereby creating a long-lasting reservoir of HIV. To gain a deeper insight into the molecular mechanisms of HIV latency establishment, we constructed a series of HIV-1 fluorescent reporter viruses that distinguish active versus latent infection.

Parenting relationships as a moderator of how socioeconomic status and household chaos relate to children's cognitive and socioemotional skills.

Low socioeconomic status (SES) and high household chaos are adverse childhood experiences (ACEs) that increase the risk of worse executive functioning (EF) and socioemotional (SE) development. EF and SE skills are foundational for lifelong success, but less is known about how positive childhood experiences (PCEs) such as parenting relationships may buffer the impact of ACEs on these important skills. This study examined how SES and household chaos related to EF and SE skills within the context of varying parenting relationships among a sample of 83 socioeconomically and racially/ethnically diverse 4- to 7-year-old children in the urban United States.

Prevalence of Specific Mood Profile Clusters among Elite and Youth Athletes at a Brazilian Sports Club.

Those responsible for elite and youth athletes are increasingly aware of the need to balance the quest for superior performance with the need to protect the physical and psychological wellbeing of athletes. As a result, regular assessment of risks to mental health is a common feature in sports organisations. In the present study, the Brazil Mood Scale (BRAMS) was administered to 898 athletes (387 female, 511 male, age range: 12-44 years) at a leading sports club in Rio de Janeiro using either "past week" or "right now" response timeframes.

Effectiveness of educational and psychological survivorship interventions to improve health-related quality of life outcomes for men with prostate cancer on androgen deprivation therapy: a systematic review.

Objectives: Androgen deprivation therapy (ADT), a common treatment for prostate cancer, has debilitating impacts on physical and psychological quality of life. While some interventions focus on managing the physical side effects of ADT, there is a paucity of interventions that also address psychosocial and educational needs. The objective of this systematic review was to identify psychological and educational survivorship interventions targeting health-related quality of life (HRQoL) outcomes in men on ADT.