3D-printed poly(ethylene) glycol diacrylate (PEGDA)-chitosan-nanohydroxyapatite scaffolds: Structural characterization and cellular response.

Polymer-based scaffolds with bioactive materials offer great potential in bone tissue engineering. Polyethylene glycol diacrylate (PEGDA) scaffolds fabricated via liquid crystal display 3D printing technique lack inherent osteoconductivity. To improve such properties, chitosan of 10 and 20 wt% and nanohydroxyapatite (nHA) (3-10 wt%) were incorporated into PEGDA scaffolds.

Concomitant Usage of H1-Antihistamines and Immune Checkpoint Inhibitors on Cancer Patient Survival.

Purpose: Recent research (Li et al. 2021) suggests an upregulated expression and activation of H1 receptors on macrophages in the tumor microenvironment, and concomitant H1-antihistamine use is associated with improved overall survival in patients with lung and skin cancers receiving immunotherapy. Therefore, we retrospectively evaluated the impacts of H1-antihistamine use in cancer patients during immunotherapy.

Intestinal TM6SF2 protects against metabolic dysfunction-associated steatohepatitis through the gut-liver axis.

Transmembrane-6 superfamily member 2 (TM6SF2) regulates hepatic fat metabolism and is associated with metabolic dysfunction-associated steatohepatitis (MASH). TM6SF2 genetic variants are associated with steatotic liver disease. The pathogenesis of MASH involves genetic factors and gut microbiota alteration, yet the role of host-microbe interactions in MASH development remains unclear.

2024 Visionary Leader Crystal Lawson.

The following article is the winning 2024 Richard Hader Visionary Leader Award entry submitted to Nursing Management in recognition of Crystal Lawson, DNP, RN, CENP, during her tenure as interim director of education at Cedars-Sinai Marina del Rey Hospital in Marina del Rey, Calif. She currently serves as CEO and founder of We Rise Up, an organization dedicated to equipping, inspiring, and empowering nurse leaders, and continues working in a leadership development consultant capacity for Cedars Sinai.