[Effect of hypoxic hypoxia on development of atherosclerosis in rabbits].

The study was aim a evaluating effects of intermittent hypoxic training on experimental atherosclerosis. In a three-month experiment rabbits (n = 12) were fed with cholesterol (200 mg/kg of the body mass) and "ascended" to the altitude of 6000 m for 6 hrs per a day. The controls (n = 10) were fed with cholesterol only.

[Thromboembolic complications in children].

An analysis was made of 2093 autopsies of children aged 0-14 years. Thromboembolic complications (TEC) were detected in 6.68% of the victims who had died from acute infections, chronic inflammatory diseases, congenital malformations.

[The surfactant system and structure of the respiratory portion of the lungs during de-adaptation following a single exposure to acute pressure chamber hypoxia].

The effect of acute pressure chamber hypoxia on the surfactant system and respiratory segment structure of the lungs were studied in rats by physical, fluorescent microscopic and morphometric methods. Acute hypoxia decreases surface activity, induces changes in cellular and extracellular surfactant fluorescence and causes the development of diffuse vesicular emphysema. On the first day of adaptation atelectatic foci dominate over emphysema, and the pulmonary structure normalizes afterwards.

[Changes in the surface activity of bronchoalveolar washings and their cellular composition in bronchial asthma].

The superficial activity and cytological composition of bronchoalveolar washes off (BAW) were investigated in 55 patients with bronchial asthma. As compared to the control group the patients with bronchial asthma in remission demonstrated a moderate decrease in the superficial BAW activity which grew in the phase of exacerbation, a degree of variations of the superficial BAW activity depending on the expression of exacerbation. Correlation between a decrease in the superficial BAW activity and changes in an endopulmonary cytogram was found.

[Surfactant system of rat lungs in acute hypoxic hypoxia].

It was shown in rat experiments made with the use of a complex of physical and histological methods and qualitative analysis that changes in the pulmonary surfactant system (PSS) during exposure to altitude chamber hypoxia depend on its duration and intensity. The preliminal effect of hypoxia determines the decrease in PSS activity. The increase in PSS activity seems to be the "emergency compensation" that develops in response to the action of the extreme threshold stimulus.