Publications by authors named "V Studentova"
Article Synopsis
- * Researchers analyzed 275 isolates from various countries using genomic techniques and found three main groups along with a proposed modified taxonomy for the genus.
- * The findings suggest significant genetic diversity among Morganella spp and highlight the importance of monitoring these pathogens' resistance mechanisms for better treatment options.
Article Synopsis
- * A total of 42 ST38 isolates were found to carry the NDM-5 gene on their chromosomes, exhibiting virulence traits like biofilm formation, which indicates their persistence.
- * Genomic analysis revealed minimal variation among isolates, suggesting a clonally driven outbreak that could pose a serious nationwide health threat.
Article Synopsis
- Sepsis is a serious global health issue linked to high mortality rates, caused by an improper immune response to infection, and can be monitored through biomarkers like procalcitonin (PCT), which can rise dramatically during severe cases.
- Researchers developed a fast detection method for PCT using MALDI-TOF mass spectrometry with specialized immuno MALDI chips, validating it against a well-known procedure (LC-MS).
- The new MALDI method successfully detected PCT in serum samples from sepsis patients, identifying not only the intact PCT but also breakdown products, indicating processing of the protein during severe infections.
The resistance to carbapenems is usually mediated by enzymes hydrolyzing β-lactam ring. Recently, an alternative way of the modification of the antibiotic, a β-lactone formation by OXA-48-like enzymes, in some carbapenems was identified. We focused our study on a deep analysis of OXA-48-like-producing Enterobacterales, especially strains showing poor hydrolytic activity.
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